Cisplatin Binding to Human Serum Transferrin: A Crystallographic Study
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DOI: 10.1021/acs.inorgchem.2c04206
Abstract: The molecular mechanism of how human serum transferrin (hTF) recognizes cisplatin at the atomic level is still unclear. Here, we report the molecular structure of the adduct formed upon the reaction of hTF with cisplatin.… read more here.
Keywords: serum transferrin; cisplatin binding; human serum;
Identification of cisplatin-binding sites on the large cytoplasmic loop of the Na+/K+-ATPase
Sign Up to like & getrecommendations! Published in 2018 at "Journal of Enzyme Inhibition and Medicinal Chemistry"
DOI: 10.1080/14756366.2018.1445735
Abstract: Abstract Cisplatin is the most widely used chemotherapeutic drug for the treatment of various types of cancer; however, its administration brings also numerous side effects. It was demonstrated that cisplatin can inhibit the Na+/K+-ATPase (NKA),… read more here.
Keywords: atpase; cisplatin; cisplatin binding; binding sites ... See more keywords