Comparative gonadotoxicity of the chemotherapy drugs cisplatin and carboplatin on prepubertal mouse gonads
Sign Up to like & getrecommendations! Published in 2020 at "Molecular Human Reproduction"
DOI: 10.1093/molehr/gaaa008
Abstract: Abstract The treatment of childhood cancer with chemotherapy drugs can result in infertility in adulthood. Newer generations of drugs are developed to replace parent drugs, with the potential benefits of less toxic side effects. For… read more here.
Keywords: chemotherapy drugs; cisplatin; cisplatin carboplatin; carboplatin ... See more keywords
Abstract 3366: APOBEC3 family of cytidine deaminases in sensitizing triple-negative breast cancer cells to cisplatin and carboplatin
Sign Up to like & getrecommendations! Published in 2018 at "Cancer Research"
DOI: 10.1158/1538-7445.am2018-3366
Abstract: Cisplatin is a DNA damaging chemotherapeutic which forms interstrand crosslinks (ICL) and intrastrand adducts that induce replication fork collapse and lead to apoptosis. These adduct sites can be repaired through several repair pathways, the most… read more here.
Keywords: cancer; cisplatin carboplatin; cytidine deaminases; family cytidine ... See more keywords
Health Impact Analysis of Cisplatin, Carboplatin and Oxaliplatin
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DOI: 10.1595/205651317x693741
Abstract: A literature based study on the health impacts of three platinum anticancer drugs (cisplatin, carboplatin and oxaliplatin) was undertaken. The published evidence for health benefits is presented and assessed. A model was developed to quantify… read more here.
Keywords: health impact; cisplatin carboplatin; impact analysis; carboplatin oxaliplatin ... See more keywords
Adverse Effects Profile of Dicycloplatin (DCP) Offers Chemotherapeutic Advantage Over Cisplatin and Carboplatin
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DOI: 10.21873/anticanres.13618
Abstract: Background/Aim: Platinum-based chemotherapy often fails due to its severe adverse effects. The aim of this study was to examine the adverse effects profile and efficacy of dicycloplatin and compare them to those of cisplatin and… read more here.
Keywords: dicycloplatin; adverse effects; effects profile; cisplatin carboplatin ... See more keywords