A low-dose pemetrexed-cisplatin combination regimen induces significant nephrotoxicity in mice compared with pemetrexed or cisplatin alone
Sign Up to like & getrecommendations! Published in 2023 at "Physiology"
DOI: 10.1152/physiol.2023.38.s1.5734918
Abstract: Pemetrexed is a cytostatic agent used to treat solid tumors and autoimmune diseases. Pemetrexed exerts its antineoplastic activity by multitargeted disruption of folate-dependent processes that mediate cell replication. Pemetrexed is now combined with cisplatin to… read more here.
Keywords: cisplatin combination; cisplatin alone; physiology; cisplatin ... See more keywords
Magrolimab and gemcitabine-cisplatin combination enhance phagocytic elimination of bladder cancer.
Sign Up to like & getrecommendations! Published in 2020 at "Journal of Clinical Oncology"
DOI: 10.1200/jco.2020.38.15_suppl.e17035
Abstract: e17035Background: CD47 is an antiphagocytic signal and macrophage checkpoint that bladder and other cancer cells over-express to evade innate immunity. Magrolimab (Hu5F9-G4) a CD47 blocking antibod... read more here.
Keywords: bladder cancer; bladder; cisplatin combination; magrolimab gemcitabine ... See more keywords