Nanopore Sequencing Accurately Identifies the Cisplatin Adduct on DNA.
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DOI: 10.1021/acssensors.1c01212
Abstract: Cisplatin, which selectively binds to N7 atoms of purines to inhibit normal replication and transcription, is a widely applied chemotherapeutic drug in the treatment of cancer. Though direct identification of cisplatin lesions on DNA is… read more here.
Keywords: sequencing accurately; dna; cisplatin lesions; cisplatin ... See more keywords