Systematic review and meta-analysis of the efficacy of clinically tested protectants of cisplatin nephrotoxicity
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DOI: 10.1007/s00228-019-02771-5
Abstract: Introduction Cisplatin is a potent antineoplastic drug that has been widely used to treat a number of solid tumors. However, a high incidence of renal damage observed in patients has led researchers to search for… read more here.
Keywords: cisplatin nephrotoxicity; analysis; systematic review; meta analysis ... See more keywords
Celastrol ameliorates cisplatin nephrotoxicity by inhibiting NF-κB and improving mitochondrial function
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DOI: 10.1016/j.ebiom.2018.09.031
Abstract: Background Celastrol is an active ingredient of Chinese medicine Tripterygium wilfordii which is clinically used to treat the immune diseases. Currently, celastrol is documented as a potent agent for treating cancer and inflammatory disorders. This… read more here.
Keywords: cisplatin nephrotoxicity; mitochondrial function; cisplatin; celastrol ... See more keywords
P0534THE EFFECT OF HIGH FAT DIET INTAKE AND FOOD SUPPLY RESTRICTION ON CISPLATIN NEPHROTOXICITY IN MICE
Sign Up to like & getrecommendations! Published in 2020 at "Nephrology Dialysis Transplantation"
DOI: 10.1093/ndt/gfaa142.p0534
Abstract: Nephrotoxicity is a major side effect of cis-diamminedichloroplatinum (II) (cisplatin), which is widely used for cancer therapy. The nephrotoxicity is associated with the excessive formation of reactive oxygen species (ROS) and oxidation of cell components.… read more here.
Keywords: cisplatin nephrotoxicity; nephrotoxicity; cisplatin; food supply ... See more keywords