Phenotypic changes on central nervous system (CNS) tumor cell lines cultured in vitro 2D and 3D models and treated with cisplatin.
Sign Up to like & getrecommendations! Published in 2021 at "Acta histochemica"
DOI: 10.1016/j.acthis.2021.151768
Abstract: Despite aggressive therapy, most patients with brain tumors present disease relapse due to the cellular and molecular nature of these tumors. One of the models that best explains the heterogeneity observed in CNS tumors is… read more here.
Keywords: treated cells; cell lines; cisplatin treated; cisplatin ... See more keywords
Revealing HOCl burst from endoplasmic reticulum in cisplatin-treated cells via a ratiometric fluorescent probe
Sign Up to like & getrecommendations! Published in 2020 at "Chinese Chemical Letters"
DOI: 10.1016/j.cclet.2020.12.039
Abstract: Abstract The reactive oxygen species (ROS) are tightly associated with endoplasmic reticulum (ER) stress. Thus, the deep and visual insight of aberrant ROS fluctuations in the ER can help us better investigate the ER stress-associated… read more here.
Keywords: hocl burst; fluorescent probe; cisplatin treated; endoplasmic reticulum ... See more keywords
Effect of cisplatin on pancreas and testies in Wistar rats: biochemical parameters and histology
Sign Up to like & getrecommendations! Published in 2019 at "Heliyon"
DOI: 10.1016/j.heliyon.2019.e02247
Abstract: Objective To investigate effect of cisplatin on biochemical parameter and histology of pancreas and testis in Wistar rats. Material and methods Single dose cisplatin (10 mg/kg) was injected by intraperitoneal route in Wistar rats. Blood… read more here.
Keywords: cisplatin treated; cisplatin; group; effect cisplatin ... See more keywords
Glutamyl aminopeptidase in microvesicular and exosomal fractions of urine is related with renal dysfunction in cisplatin-treated rats
Sign Up to like & getrecommendations! Published in 2017 at "PLoS ONE"
DOI: 10.1371/journal.pone.0175462
Abstract: Purpose The aim of this work was to investigate if the content of glutamyl aminopeptidase (GluAp) in microvesicular and exosomal fractions of urine is related with renal dysfunction in cisplatin-treated rats. Methods Urine samples were… read more here.
Keywords: cisplatin treated; exosomal fractions; treated rats; fractions urine ... See more keywords
MMG22 Potently Blocks Hyperalgesia in Cisplatin-treated Mice
Sign Up to like & getrecommendations! Published in 2023 at "Neuroscience"
DOI: 10.2139/ssrn.4192510
Abstract: MMG22 is a bivalent ligand containing MOR agonist and mGluR5 antagonist pharmacophores connected by a 22-atom linker. Intrathecal (i.t.) administration of MMG22 to inflamed mice has been reported to produce fmol-range antinociception in the reversal… read more here.
Keywords: cisplatin treated; mmg22; hyperalgesia; potently blocks ... See more keywords
Melatonin Mitigates Cisplatin-Induced Ovarian Dysfunction via Altering Steroidogenesis, Inflammation, Apoptosis, Oxidative Stress, and PTEN/PI3K/Akt/mTOR/AMPK Signaling Pathway in Female Rats
Sign Up to like & getrecommendations! Published in 2022 at "Pharmaceutics"
DOI: 10.3390/pharmaceutics14122769
Abstract: Ovarian damage and fertility impairment are major side effects of chemotherapy in pre-menopausal cancer patients. Cisplatin is a widely used chemotherapeutic drug. The present study was designed to assess the ameliorative effects of melatonin as… read more here.
Keywords: akt mtor; cisplatin treated; pi3k akt; cisplatin ... See more keywords