Investigating Population‐Level Toxicity of the Antidepressant Citalopram in Harpacticoid Copepods Using In Vivo Methods and Bioenergetics‐Based Population Modeling
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DOI: 10.1002/etc.5599
Abstract: Recent research has revealed various lethal and sublethal effects of the selective serotonin reuptake inhibitor citalopram hydrobromide on the harpacticoid copepod Nitocra spinipes. In the present study, an individual‐based model (IBM) grounded in the dynamic… read more here.
Keywords: citalopram; population level; bioenergetics based; model ... See more keywords
The SSRI citalopram increases the sensitivity of the human circadian system to light in an acute dose
Sign Up to like & getrecommendations! Published in 2018 at "Psychopharmacology"
DOI: 10.1007/s00213-018-5019-0
Abstract: RationaleDisturbances of the circadian system are common in depression. Though they typically subside when depression is treated with antidepressants, the mechanism by which this occurs is unknown. Despite being the most commonly prescribed class of… read more here.
Keywords: human circadian; circadian system; sensitivity; citalopram ... See more keywords
Citalopram restores short-term memory deficit and non-cognitive behaviors in APP/PS1 mice while halting the advance of Alzheimer's disease-like pathology
Sign Up to like & getrecommendations! Published in 2018 at "Neuropharmacology"
DOI: 10.1016/j.neuropharm.2017.12.021
Abstract: ABSTRACT Alzheimer's disease (AD) is the most common cause of dementia. In addition to cognitive impairments, deficits in non‐cognitive behaviors are also common neurological sequelae in AD. Here, we show that complex behavioral deficits in… read more here.
Keywords: short term; ps1 mice; pathology; citalopram ... See more keywords
Long-Term Exposure to SSRI Citalopram Induces Neurotoxic Effects in Zebrafish.
Sign Up to like & getrecommendations! Published in 2022 at "Environmental science & technology"
DOI: 10.1021/acs.est.2c01514
Abstract: Residual antidepressants are of increasing concern worldwide, yet critical information on their long-term neurotoxic impacts on nontarget aquatic animals is lacking. Here, we investigated the long-term effects (from 0 to 150 days postfertilization) of the… read more here.
Keywords: long term; citalopram; motor; term exposure ... See more keywords
Effects of a combination of Nigella sativa and Vitex agnus-castus with citalopram on healthy menopausal women with hot flashes: results from a subpopulation analysis
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DOI: 10.1080/09513590.2018.1499086
Abstract: Abstract The goal of the current study was to evaluate the efficiency of a phytotherapeutic intervention consisting of a combination of Nigella sativa and Vitex agnus-castus with citalopram in the control of hot flashes in… read more here.
Keywords: combination; hot flashes; citalopram; castus citalopram ... See more keywords
Inhibitory Effect of Citalopram on the Pharmacokinetics of Carvedilol in Rats and in vitro Models
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DOI: 10.1159/000480090
Abstract: Background/Aims: The aim of this study was to investigate the drug-drug interaction between carvedilol and citalopram based on carvedilol metabolism in vitro and his pharmacokinetics (PKs) in vivo after the oral administration of the single… read more here.
Keywords: administration; drug; carvedilol; citalopram ... See more keywords
Neuroregeneration and Vascular Protection by Citalopram in Acute Ischemic Stroke (TALOS): A Randomized Controlled Study
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DOI: 10.1161/strokeaha.117.020067
Abstract: Background and Purpose— Recent studies indicate a possible beneficial effect on neuroregeneration and vascular protection of selective serotonin reuptake inhibitors after stroke. We conducted a national multicentre study to explore these effects. Methods— The TALOS… read more here.
Keywords: protection; ischemic stroke; treatment; study ... See more keywords
Effect of transcranial magnetic stimulation in combination with citalopram on patients with post-stroke depression
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DOI: 10.3389/fnhum.2022.962231
Abstract: Background Amelioration of depression in patients with post-stroke depression (PSD) remains challenging. Objective The primary vision was to explore the effect of transcranial magnetic stimulation (TMS) in combination with citalopram on patients with PSD. Methods… read more here.
Keywords: combination citalopram; depression; group; citalopram patients ... See more keywords
Citalopram-induced sleep bruxism in a breastfed infant: A case report
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DOI: 10.3389/fpsyt.2023.1051346
Abstract: Bruxism associated with antidepressant use is an under-recognized phenomenon. The use of citalopram has gained wide acceptance in the treatment of depression and anxiety disorders; however, the consumption of this medication during lactation and pregnancy… read more here.
Keywords: breastfed infant; sleep bruxism; induced sleep; bruxism ... See more keywords
Aqueous Extract of Pomegranate Alone or in Combination with Citalopram Produces Antidepressant-Like Effects in an Animal Model of Menopause: Participation of Estrogen Receptors
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DOI: 10.3390/ijms18122643
Abstract: It has been reported that the aqueous extract of pomegranate (AE-PG) has polyphenols with estrogenic-like activities. The present work determines if AE-PG alone or in combination with the selective serotonin reuptake inhibitor, citalopram, has antidepressant-like… read more here.
Keywords: participation; like effects; antidepressant like; citalopram ... See more keywords
Chronic Trazodone and Citalopram Treatments Increase Trophic Factor and Circadian Rhythm Gene Expression in Rat Brain Regions Relevant for Antidepressant Efficacy
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DOI: 10.3390/ijms232214041
Abstract: Trazodone is an efficacious atypical antidepressant acting both as an SSRI and a 5HT2A and 5HT2C antagonist. Antagonism to H1-histaminergic and alpha1-adrenergic receptors is responsible for a sleep-promoting action. We studied long-term gene expression modulations… read more here.
Keywords: chronic trazodone; expression; citalopram; circadian rhythm ... See more keywords