Hepatic intravital imaging reveals the contribution of peptidylarginine deiminase 4 (PAD4) to the spatiotemporal dynamics of neutrophil recruitment and NET release during bacterial infection
Sign Up to like & getrecommendations! Published in 2025 at "Blood"
DOI: 10.1182/blood-2025-1221
Abstract: Background: Intravital imaging is a powerful tool for investigating dynamic biologic processes such as neutrophil (PMN) recruitment and NETs release during infection. However, the specificity of commonly used NETosis markers remains uncertain. Histone H2AX and… read more here.
Keywords: h2ax; cith3; padi4 mice; infection ... See more keywords
Citrullinated Histone H3 as a Therapeutic Target for Endotoxic Shock in Mice
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DOI: 10.3389/fimmu.2019.02957
Abstract: Sepsis results in millions of deaths every year, with acute lung injury (ALI) being one of the leading causes of mortality in septic patients. As neutrophil extracellular traps (NETs) are abundant in sepsis, neutralizing components… read more here.
Keywords: cith3; citrullinated histone; histone therapeutic; therapeutic target ... See more keywords