Suppressed de novo lipogenesis by plasma membrane citrate transporter inhibitor promotes apoptosis in HepG2 cells
Sign Up to like & getrecommendations! Published in 2018 at "FEBS Open Bio"
DOI: 10.1002/2211-5463.12435
Abstract: Suppression of the expression or activities of enzymes that are involved in the synthesis of de novo lipogenesis (DNL) in cancer cells triggers cell death via apoptosis. The plasma membrane citrate transporter (PMCT) is the… read more here.
Keywords: citrate; apoptosis; hepg2 cells; pmcti ... See more keywords
Metabolic‐Efferocytosis Enabled Hydrogel Synergism Reprograms Immune Microenvironment for Promoting Diabetic Wound Repair
Sign Up to like & getrecommendations! Published in 2025 at "Advanced Functional Materials"
DOI: 10.1002/adfm.202420079
Abstract: Diabetic wound healing remains a significant challenge, due to chronic inflammatory apoptotic cells accumulation. Herein, an immuno‐bioenergy regulated hydrogel (CCE) is reported, which converts apoptotic cells into cytokines that facilitate tissue repair. The CCE consisted… read more here.
Keywords: diabetic wound; repair; efferocytosis; citrate ... See more keywords
Bioactive Poly(octanediol-citrate-polyglycol) Accelerates Skin Regeneration through M2 Polarization Immunomodulating and Early Angiogenesis.
Sign Up to like & getrecommendations! Published in 2022 at "Advanced healthcare materials"
DOI: 10.1002/adhm.202101931
Abstract: The inhibition of inflammation and the promotion of early angiogenesis have been paid much attention in skin tissue engineering. Citric acid-based biomaterials are widely used in tissue engineering due to their bioactive structure and biocompatibility,… read more here.
Keywords: citrate; angiogenesis; polarization; skin regeneration ... See more keywords
A Novel Poly(Diol Citrate) Containing N‐Hydroxysuccinimide Ester: Synthesis and Its Enabled Hydrogel Adhesive
Sign Up to like & getrecommendations! Published in 2025 at "Journal of Applied Polymer Science"
DOI: 10.1002/app.57001
Abstract: Recently developed catechol‐modified poly(diol citrate)‐based adhesives behaved with a good biological properties and wet adhesive ability. However, a strong oxidant (e.g., sodium periodate) was inevitably required to promote solidification during bonding tissues, which would jeopardize… read more here.
Keywords: poly diol; poec; diol citrate; citrate ... See more keywords
Comprehensive Improvement of Sample Preparation Methodologies Facilitates Dynamic Metabolomics of Aspergillus niger.
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DOI: 10.1002/biot.201800315
Abstract: Metabolomics is an essential discipline in industrial biotechnology. Sample preparation approaches dramatically influence data quality and, ultimately, interpretation and conclusions from metabolomic experiments. However, standardized protocols for highly reproducible metabolic datasets are limited, especially for… read more here.
Keywords: sample preparation; methodology; aspergillus niger; citrate ... See more keywords
Bioequivalence and Bioavailability of an Orodispersible Tablet of Sildenafil Citrate in Healthy Chinese Male Subjects
Sign Up to like & getrecommendations! Published in 2020 at "Clinical Pharmacology in Drug Development"
DOI: 10.1002/cpdd.806
Abstract: Sildenafil citrate is approved to treat erectile dysfunction. An orally disintegrating tablet (ODT) of sildenafil citrate that does not require swallowing or administration with fluids has been developed. The bioequivalence and bioavailability of sildenafil citrate… read more here.
Keywords: bioequivalence; healthy chinese; citrate; water ... See more keywords
Cellular citrate levels establish a regulatory link between energy metabolism and the hepatic iron hormone hepcidin
Sign Up to like & getrecommendations! Published in 2017 at "Journal of Molecular Medicine"
DOI: 10.1007/s00109-017-1551-3
Abstract: Expression of the hepatic peptide hormone hepcidin responds to iron levels via BMP/SMAD signaling, to inflammatory cues via JAK/STAT signaling, to the nutrient-sensing mTOR pathway, as well as to proliferative signals and gluconeogenesis. Here, we… read more here.
Keywords: citrate; metabolism; hormone hepcidin; expression ... See more keywords
Identification and importance of mitochondrial citrate carriers and ATP citrate lyase for glycolipid production in Starmerella bombicola
Sign Up to like & getrecommendations! Published in 2020 at "Applied Microbiology and Biotechnology"
DOI: 10.1007/s00253-020-10702-z
Abstract: Starmerella bombicola is a non-conventional yeast commercially used as a microbial cell factory for sophorolipid production. Sophorolipids are glycolipid biosurfactants composed of a glucose disaccharide sophorose and a fatty acid. In de novo sophorolipid synthesis,… read more here.
Keywords: production; mitochondrial carriers; citrate; starmerella bombicola ... See more keywords
The effect of hydroxyalkyls, derivatives of 2-hydroxypropane-1.2.3-tricarboxylic acid, on flammability and thermal properties of PUR–PIR foams
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DOI: 10.1007/s00289-017-2191-z
Abstract: This article describes the results of multidirectional research on the flammability and heat properties of rigid polyurethane–polyisocyanurate foams (PUR–PIR). They were produced, using new three polyols (citrates) obtained from 2-hydroxypropane-1.2.3-tricarboxylic acid (citric) and selected diols:… read more here.
Keywords: flammability; acid; diol; citrate ... See more keywords
Effect of citrate anion incorporation on dielectric properties of anodic oxide grown on Ti-Si alloy
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DOI: 10.1007/s10008-024-06087-y
Abstract: Anodic oxides were galvanostatically grown on sputtered Ti-12at%Si alloy at 5 mA cm−2 up to 50 V in phosphoric acid and sodium citrate aqueous electrolytes in order to investigate the effect of anions incorporation (if… read more here.
Keywords: effect; incorporation dielectric; citrate; anodic oxide ... See more keywords
Efficacy and safety of ferric citrate hydrate compared with sodium ferrous citrate in Japanese patients with iron deficiency anemia: a randomized, double-blind, phase 3 non-inferiority study
Sign Up to like & getrecommendations! Published in 2021 at "International Journal of Hematology"
DOI: 10.1007/s12185-021-03123-9
Abstract: Oral iron preparations are used as first-line treatment for iron deficiency anemia (IDA), but their gastrointestinal side effects prevent patients from appropriate adherence. We recently conducted a randomized, double-blind, phase 3 non-inferiority study to evaluate… read more here.
Keywords: randomized double; citrate; efficacy; deficiency anemia ... See more keywords