Suppressed de novo lipogenesis by plasma membrane citrate transporter inhibitor promotes apoptosis in HepG2 cells
Sign Up to like & getrecommendations! Published in 2018 at "FEBS Open Bio"
DOI: 10.1002/2211-5463.12435
Abstract: Suppression of the expression or activities of enzymes that are involved in the synthesis of de novo lipogenesis (DNL) in cancer cells triggers cell death via apoptosis. The plasma membrane citrate transporter (PMCT) is the… read more here.
Keywords: citrate; apoptosis; hepg2 cells; pmcti ... See more keywords
Bioactive Poly(octanediol-citrate-polyglycol) Accelerates Skin Regeneration through M2 Polarization Immunomodulating and Early Angiogenesis.
Sign Up to like & getrecommendations! Published in 2022 at "Advanced healthcare materials"
DOI: 10.1002/adhm.202101931
Abstract: The inhibition of inflammation and the promotion of early angiogenesis have been paid much attention in skin tissue engineering. Citric acid-based biomaterials are widely used in tissue engineering due to their bioactive structure and biocompatibility,… read more here.
Keywords: citrate; angiogenesis; polarization; skin regeneration ... See more keywords
Comprehensive Improvement of Sample Preparation Methodologies Facilitates Dynamic Metabolomics of Aspergillus niger.
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DOI: 10.1002/biot.201800315
Abstract: Metabolomics is an essential discipline in industrial biotechnology. Sample preparation approaches dramatically influence data quality and, ultimately, interpretation and conclusions from metabolomic experiments. However, standardized protocols for highly reproducible metabolic datasets are limited, especially for… read more here.
Keywords: sample preparation; methodology; aspergillus niger; citrate ... See more keywords
Bioequivalence and Bioavailability of an Orodispersible Tablet of Sildenafil Citrate in Healthy Chinese Male Subjects
Sign Up to like & getrecommendations! Published in 2020 at "Clinical Pharmacology in Drug Development"
DOI: 10.1002/cpdd.806
Abstract: Sildenafil citrate is approved to treat erectile dysfunction. An orally disintegrating tablet (ODT) of sildenafil citrate that does not require swallowing or administration with fluids has been developed. The bioequivalence and bioavailability of sildenafil citrate… read more here.
Keywords: bioequivalence; healthy chinese; citrate; water ... See more keywords
Cellular citrate levels establish a regulatory link between energy metabolism and the hepatic iron hormone hepcidin
Sign Up to like & getrecommendations! Published in 2017 at "Journal of Molecular Medicine"
DOI: 10.1007/s00109-017-1551-3
Abstract: Expression of the hepatic peptide hormone hepcidin responds to iron levels via BMP/SMAD signaling, to inflammatory cues via JAK/STAT signaling, to the nutrient-sensing mTOR pathway, as well as to proliferative signals and gluconeogenesis. Here, we… read more here.
Keywords: citrate; metabolism; hormone hepcidin; expression ... See more keywords
Identification and importance of mitochondrial citrate carriers and ATP citrate lyase for glycolipid production in Starmerella bombicola
Sign Up to like & getrecommendations! Published in 2020 at "Applied Microbiology and Biotechnology"
DOI: 10.1007/s00253-020-10702-z
Abstract: Starmerella bombicola is a non-conventional yeast commercially used as a microbial cell factory for sophorolipid production. Sophorolipids are glycolipid biosurfactants composed of a glucose disaccharide sophorose and a fatty acid. In de novo sophorolipid synthesis,… read more here.
Keywords: production; mitochondrial carriers; citrate; starmerella bombicola ... See more keywords
The effect of hydroxyalkyls, derivatives of 2-hydroxypropane-1.2.3-tricarboxylic acid, on flammability and thermal properties of PUR–PIR foams
Sign Up to like & getrecommendations! Published in 2017 at "Polymer Bulletin"
DOI: 10.1007/s00289-017-2191-z
Abstract: This article describes the results of multidirectional research on the flammability and heat properties of rigid polyurethane–polyisocyanurate foams (PUR–PIR). They were produced, using new three polyols (citrates) obtained from 2-hydroxypropane-1.2.3-tricarboxylic acid (citric) and selected diols:… read more here.
Keywords: flammability; acid; diol; citrate ... See more keywords
Efficacy and safety of ferric citrate hydrate compared with sodium ferrous citrate in Japanese patients with iron deficiency anemia: a randomized, double-blind, phase 3 non-inferiority study
Sign Up to like & getrecommendations! Published in 2021 at "International Journal of Hematology"
DOI: 10.1007/s12185-021-03123-9
Abstract: Oral iron preparations are used as first-line treatment for iron deficiency anemia (IDA), but their gastrointestinal side effects prevent patients from appropriate adherence. We recently conducted a randomized, double-blind, phase 3 non-inferiority study to evaluate… read more here.
Keywords: randomized double; citrate; efficacy; deficiency anemia ... See more keywords
Control of metabolic predisposition to cardiovascular complications of chronic kidney disease by effervescent calcium magnesium citrate: a feasibility study
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DOI: 10.1007/s40620-018-0559-2
Abstract: AimsCardiovascular (CV) complications are common in chronic kidney disease (CKD). Numerous metabolic disturbances including hyperphosphatemia, high circulating calciprotein particles (CPP), hyperparathyroidism, metabolic acidosis, and magnesium deficiency are associated with, and likely pathogenic for CV complications… read more here.
Keywords: citrate; study; caac; magnesium ... See more keywords
Experimental determination of solubilities of tri-calcium di-citrate tetrahydrate [Ca3[C3H5O(COO)3]2•4H2O], earlandite, in NaCl and MgCl2 solutions to high ionic strengths
Sign Up to like & getrecommendations! Published in 2020 at "Applied Geochemistry"
DOI: 10.1016/j.apgeochem.2020.104856
Abstract: Abstract In this study, solubility measurements on tri-calcium di-citrate tetrahydrate [Ca3[C3H5O(COO)3]2•4H2O, abbreviated as Ca3[Citrate]2•4H2O, earlandite] as a function of ionic strength are conducted in NaCl solutions up to I = 5.0 mol•kg–1 and in MgCl2… read more here.
Keywords: calcium citrate; ca3; c3h5o coo; citrate ... See more keywords
Biotechnological purification of a β-fructofuranosidase (β-FFase) from Aspergillus tamarii kita: Aqueous two-phase system (PEG/Citrate) and biochemical characterization
Sign Up to like & getrecommendations! Published in 2021 at "Biocatalysis and Agricultural Biotechnology"
DOI: 10.1016/j.bcab.2021.102070
Abstract: Abstract β-fructofuranosidases (EC3.2.1.26) are members of the GH32 family of glycoside hydrolases, which include more than 390 enzymes of vegetable and microbial origins, used in several biotechnological applications. Thus, this research aimed to produce a… read more here.
Keywords: phase; fructofuranosidase; citrate; aspergillus tamarii ... See more keywords