The Mouse Model of Infection with Citrobacter rodentium
Sign Up to like & getrecommendations! Published in 2017 at "Current Protocols in Immunology"
DOI: 10.1002/cpim.34
Abstract: Citrobacter rodentium is a murine mucosal pathogen used as a model to elucidate the molecular and cellular pathogenesis of infection with two clinically important human gastrointestinal pathogens, enteropathogenic Escherichia coli (EPEC) and enterohaemorrhagic E. coli… read more here.
Keywords: rodentium; infection; mouse model; citrobacter rodentium ... See more keywords
R18C is a new viable P2-like bacteriophage of rabbit origin infecting Citrobacter rodentium and Shigella sonnei strains
Sign Up to like & getrecommendations! Published in 2019 at "Archives of Virology"
DOI: 10.1007/s00705-019-04424-5
Abstract: Here, we report a novel virulent P2-like bacteriophage, R18C, isolated from rabbit faeces, which, in addition to Escherichia coli K-12 strains, was able to be propagated on Citrobacter rodentium strain ICC169 and a range of… read more here.
Keywords: like bacteriophage; citrobacter rodentium; bacteriophage; rabbit ... See more keywords
Regulation of Citrobacter rodentium colonization: virulence, immune response and microbiota interactions.
Sign Up to like & getrecommendations! Published in 2021 at "Current opinion in microbiology"
DOI: 10.1016/j.mib.2021.07.003
Abstract: Citrobacter rodentium is a mouse-specific pathogen commonly used to model infection by human Enteropathogenic Escherichia coli, an important cause of infant diarrhea and mortality worldwide. In the early phase of infection, C. rodentium overcomes competition… read more here.
Keywords: microbiota; citrobacter rodentium; colonization; immune response ... See more keywords
Protective effects of oral immunization with formalin-inactivated whole-cell Citrobacter rodentium on Citrobacter rodentium infection in mice.
Sign Up to like & getrecommendations! Published in 2019 at "Journal of microbiological methods"
DOI: 10.1016/j.mimet.2019.02.016
Abstract: Evaluation of the efficacy of vaccine candidates that prevent enteropathogenic and enterohemorrhagic Escherichia coli (EPEC/EHEC) infection in mouse models is difficult due to their limited pathogenicity in mice. Citrobacter rodentium, a murine pathogenic bacterium that… read more here.
Keywords: citrobacter rodentium; rodentium infection; infection; mice ... See more keywords
Characterization of the intestinal microbiota during Citrobacter rodentium infection in a mouse model of infection-triggered Parkinson’s disease
Sign Up to like & getrecommendations! Published in 2020 at "Gut Microbes"
DOI: 10.1080/19490976.2020.1830694
Abstract: ABSTRACT Parkinson’s disease (PD) is a neurodegenerative disorder that has been shown to be influenced by the intestinal milieu. The gut microbiota is altered in PD patients, and murine studies have begun suggesting a causative… read more here.
Keywords: microbiota; citrobacter rodentium; rodentium infection; infection ... See more keywords
GPR120 promotes neutrophil control of intestinal bacterial infection
Sign Up to like & getrecommendations! Published in 2023 at "Gut Microbes"
DOI: 10.1080/19490976.2023.2190311
Abstract: ABSTRACT G-protein coupled receptor 120 (GPR 120) has been implicated in anti-inflammatory functions. However, how GPR120 regulates the neutrophil function remains unknown. This study investigated the role of GPR120 in the regulation of neutrophil function… read more here.
Keywords: gpr120; infection; mice; citrobacter rodentium ... See more keywords
Distinct Molecular Features of NleG Type 3 Secreted Effectors Allow for Different Roles during Citrobacter rodentium Infection in Mice
Sign Up to like & getrecommendations! Published in 2022 at "Infection and Immunity"
DOI: 10.1128/iai.00505-22
Abstract: The NleGs are the largest family of type 3 secreted effectors in attaching and effacing (A/E) pathogens, such as enterohemorrhagic Escherichia coli (EHEC), enteropathogenic E. coli, and Citrobacter rodentium. NleG effectors contain a conserved C-terminal… read more here.
Keywords: infection; domain; type secreted; citrobacter rodentium ... See more keywords
Inflammasome Activation by ATP Enhances Citrobacter rodentium Clearance through ROS Generation
Sign Up to like & getrecommendations! Published in 2017 at "Cellular Physiology and Biochemistry"
DOI: 10.1159/000455988
Abstract: Background: Nod-like receptor family, pyrin domain containing 3 (NLRP3) is an important cytosolic sensor of cellular stress and infection. Once activated, NLRP3 forms a multiprotein complex (inflammasome) that triggers the maturation and secretion of interleukin… read more here.
Keywords: atp; inflammasome activation; citrobacter rodentium; infection ... See more keywords
Colonic levels of vasoactive intestinal peptide decrease during infection and exogenous VIP protects epithelial mitochondria against the negative effects of IFNγ and TNFα induced during Citrobacter rodentium infection
Sign Up to like & getrecommendations! Published in 2018 at "PLoS ONE"
DOI: 10.1371/journal.pone.0204567
Abstract: Citrobacter rodentium infection is a model for infection with attaching and effacing pathogens, such as enteropathogenic Escherichia coli. The vasoactive intestinal peptide (VIP) has emerged as an anti-inflammatory agent, documented to inhibit Th1 immune responses… read more here.
Keywords: vip; citrobacter rodentium; rodentium infection; infection ... See more keywords
The Citrobacter rodentium type III secretion system effector EspO affects mucosal damage repair and antimicrobial responses
Sign Up to like & getrecommendations! Published in 2018 at "PLoS Pathogens"
DOI: 10.1371/journal.ppat.1007406
Abstract: Infection with Citrobacter rodentium triggers robust tissue damage repair responses, manifested by secretion of IL-22, in the absence of which mice succumbed to the infection. Of the main hallmarks of C. rodentium infection are colonic… read more here.
Keywords: secretion; citrobacter rodentium; infection; rodentium ... See more keywords
T-cell derived acetylcholine aids host defenses during enteric bacterial infection with Citrobacter rodentium
Sign Up to like & getrecommendations! Published in 2019 at "PLoS Pathogens"
DOI: 10.1371/journal.ppat.1007719
Abstract: The regulation of mucosal immune function is critical to host protection from enteric pathogens but is incompletely understood. The nervous system and the neurotransmitter acetylcholine play an integral part in host defense against enteric bacterial… read more here.
Keywords: citrobacter rodentium; infection; enteric bacterial; expression ... See more keywords