Antibodies against citrullinated peptides are associated with clinical and radiological outcomes in patients with early rheumatoid arthritis: a prospective longitudinal inception cohort study
Sign Up to like & getrecommendations! Published in 2019 at "RMD Open"
DOI: 10.1136/rmdopen-2019-000946
Abstract: Introduction Anticitrullinated peptide antibody (ACPA) responses for 22 citrullinated peptides in patients with early rheumatoid arthritis (RA) were analysed and related to radiological and clinical outcome during the first 2 years in a prospective inception… read more here.
Keywords: patients early; acpa reactivities; early rheumatoid; rheumatoid arthritis ... See more keywords
Immunomodulation of RA Patients' PBMC with a Multiepitope Peptide Derived from Citrullinated Autoantigens
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DOI: 10.1155/2017/3916519
Abstract: Citrullinated peptides are used for measuring anticitrullinated protein antibodies (ACPA) in rheumatoid arthritis (RA). Accumulation of citrullinated proteins in the inflamed synovium suggests that they may be good targets for inducing peripheral tolerance. In view… read more here.
Keywords: peptide; cit; immunomodulation patients; expression ... See more keywords
Detection of salivary citrullinated cytokeratin 13 in healthy individuals and patients with rheumatoid arthritis by proteomics analysis
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DOI: 10.1371/journal.pone.0265687
Abstract: The immune response to citrullinated peptides in the mucosa has been suggested to play an important role in the transition from pre-onset rheumatoid arthritis (RA) to clinically evident RA. Although there are reports indicating the… read more here.
Keywords: rheumatoid arthritis; citrullinated peptides; cit ck13; detection ... See more keywords
How RA Associated HLA-DR Molecules Contribute to the Development of Antibodies to Citrullinated Proteins: The Hapten Carrier Model
Sign Up to like & getrecommendations! Published in 2022 at "Frontiers in Immunology"
DOI: 10.3389/fimmu.2022.930112
Abstract: The risk to develop ACPA positive rheumatoid arthritis (RA), the most destructive type of autoimmune arthritis, is carried by HLA-DRB1 alleles containing a 5 amino acid motif: the shared epitope (SE). RA is preceded by… read more here.
Keywords: citrullinated peptides; carrier; hla; hapten carrier ... See more keywords