Detection of anti-citrullinated protein antibody (ACPA) in saliva for rheumatoid arthritis using DBA mice infected with Porphyromonas gingivalis.
Sign Up to like & getrecommendations! Published in 2019 at "Archives of oral biology"
DOI: 10.1016/j.archoralbio.2019.104510
Abstract: OBJECTIVE The anti-citrullinated protein antibody (ACPA), an autoantibody of rheumatoid arthritis (RA), is very specific in the diagnosis of RA and has been detected in early cases and several years before the onset of the… read more here.
Keywords: arthritis; saliva; anti citrullinated; citrullinated protein ... See more keywords
Salivary citrullinated proteins in rheumatoid arthritis and associated periodontal disease
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DOI: 10.1038/s41598-021-93008-y
Abstract: Periodontal disease (PD) can be an important precipitating factor in the production of citrullinated proteins. Its importance is emphasized, but it is not the only way to produce citrullinated proteins. The aim of the current… read more here.
Keywords: periodontal disease; citrullinated proteins; disease; citrullinated protein ... See more keywords
Anti-citrullinated protein antibody profiles predict changes in disease activity in patients with rheumatoid arthritis initiating biologics.
Sign Up to like & getrecommendations! Published in 2023 at "Rheumatology"
DOI: 10.1093/rheumatology/kead260
Abstract: OBJECTIVES To determine whether an expanded antigen-specific anti-citrullinated protein antibody (ACPA) profile predicts changes in disease activity in patients with rheumatoid arthritis (RA) initiating biologics. METHODS The study included participants from a prospective, non-randomized, observational… read more here.
Keywords: citrullinated protein; protein antibody; anti citrullinated; treatment ... See more keywords
Current view on the pathogenic role of anti-citrullinated protein antibodies in rheumatoid arthritis
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DOI: 10.1136/rmdopen-2020-001228
Abstract: Epidemiological findings suggest a potential role for anti-citrullinated protein antibodies (ACPAs) in rheumatoid arthritis (RA) pathogenesis. ACPA-positive RA is associated with unique genetical and environmental risk factors, in contrast to seronegative RA. ACPA-positive healthy individuals… read more here.
Keywords: protein antibodies; anti citrullinated; citrullinated protein; role anti ... See more keywords
Anti-citrullinated Protein Antibody Generation, Pathogenesis, Clinical Application, and Prospects
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DOI: 10.3389/fmed.2021.802934
Abstract: Anti-citrullinated protein antibodies (ACPAs) are autoantibodies commonly observed in patients with rheumatoid arthritis (RA). Currently, most of the mechanisms of ACPA formation and bone destruction are well-understood, however, some unknown mechanisms still exist. There have… read more here.
Keywords: application prospects; citrullinated protein; anti citrullinated; clinical application ... See more keywords
Anti-Citrullinated Protein Antibody Reactivity towards Neutrophil-Derived Antigens: Clonal Diversity and Inter-Individual Variation
Sign Up to like & getrecommendations! Published in 2023 at "Biomolecules"
DOI: 10.3390/biom13040630
Abstract: Background: Why the adaptive immune system turns against citrullinated antigens in rheumatoid arthritis (RA) and whether anti-citrullinated protein antibodies (ACPAs) contribute to pathogenesis are questions that have triggered intense research, but still are not fully… read more here.
Keywords: citrullinated protein; neutrophil derived; clonal diversity; anti citrullinated ... See more keywords