Silencing CK19 regulates ferroptosis by affecting the expression of GPX4 and ACSL4 in oral squamous cell carcinoma in vivo and in vitro
Sign Up to like & getrecommendations! Published in 2024 at "Scientific Reports"
DOI: 10.1038/s41598-024-65079-0
Abstract: To analyze the mechanism of how interfering with the cytokeratin 19 (CK19) pathway via the ferroptosis pathway affects tumor biological behaviors in the process of oral squamous cell carcinoma (OSCC) development. TCGA was used to… read more here.
Keywords: silencing ck19; cell carcinoma; ferroptosis; squamous cell ... See more keywords
Imaging Features of Gadoxetic Acid-enhanced and Diffusion-weighted MR Imaging for Identifying Cytokeratin 19-positive Hepatocellular Carcinoma: A Retrospective Observational Study.
Sign Up to like & getrecommendations! Published in 2018 at "Radiology"
DOI: 10.1148/radiol.2017162846
Abstract: Purpose To determine the preoperative magnetic resonance (MR) imaging findings potentially most useful for predicting cytokeratin 19 (CK19)-positive hepatocellular carcinoma (HCC) and to evaluate the prognosis after curative resection in patients with a single HCC… read more here.
Keywords: ck19; ck19 positive; enhanced diffusion; acid enhanced ... See more keywords
Gadoxetic Acid-Enhanced MRI-Based Radiomics Signature: A Potential Imaging Biomarker for Identifying Cytokeratin 19-Positive Hepatocellular Carcinoma
Sign Up to like & getrecommendations! Published in 2023 at "Computational and Mathematical Methods in Medicine"
DOI: 10.1155/2023/5424204
Abstract: Purpose One subtype of hepatocellular carcinoma (HCC), with cytokeratin 19 expression (CK19+), has shown to be more aggressive and has a poor prognosis. However, CK19+ is determined by immunohistochemical examination using a surgically resected specimen.… read more here.
Keywords: radiomics signature; ck19; gadoxetic acid; acid enhanced ... See more keywords
Abstract 2240: CK19 based molecular classification defined three distinct hepatocellular carcinoma subtypes with different cell lineage features and therapeutic vulnerabilities
Sign Up to like & getrecommendations! Published in 2023 at "Cancer Research"
DOI: 10.1158/1538-7445.am2023-2240
Abstract: Purpose: CK19 has been recognized as an important molecular marker for poor prognosis of Hepatocellular carcinoma (HCC), however, its molecular determinants and clinical implications is still remains a largely unmet challenge. We sought to identify… read more here.
Keywords: cell; hcc; different cell; cell lineage ... See more keywords
Comparing the computed tomography radiologic features of cytokeratin 19-positive hepatocellular carcinoma to those of conventional hepatocellular carcinoma and intrahepatic cholangiocarcinoma
Sign Up to like & getrecommendations! Published in 2025 at "Quantitative Imaging in Medicine and Surgery"
DOI: 10.21037/qims-24-914
Abstract: Background Cytokeratin 19-positive hepatocellular carcinoma (CK19+ HCC) is an uncommon subtype of hepatocellular carcinoma (HCC). The purpose of this study was to identify radiological characteristics with diagnostic value for CK19+ HCC. Methods This was a… read more here.
Keywords: hepatocellular carcinoma; cytokeratin positive; ck19; ck19 hcc ... See more keywords
CK19 Promotes Ovarian Cancer Development by Impacting on Wnt/β-Catenin Pathway
Sign Up to like & getrecommendations! Published in 2020 at "OncoTargets and therapy"
DOI: 10.2147/ott.s242778
Abstract: Background Epithelial ovarian cancer (EOC) is the most common type of ovarian cancer and is the most lethal gynecologic malignancy. Cytokeratin 19 (CK19) is a small type I cytokeratin. The aim of this study is… read more here.
Keywords: ck19; wnt catenin; ovarian cancer; cancer ... See more keywords
Quantitative CK19 biomarker detection in breast cancer cell lines
Sign Up to like & getrecommendations! Published in 2022 at "Journal of Medicine and Life"
DOI: 10.25122/jml-2021-1101
Abstract: Cytokeratin19 (CK19) was detected as the most related marker for circulating tumor cells, which was assessed in specific cell lines. MCF7, SKBR3, T47D, and MDA-MB-231, and HeLa cell line as negative control were used. CK19… read more here.
Keywords: cell; breast; ck19; ck19 expression ... See more keywords
Cadherin 17 is related to recurrence and poor prognosis of cytokeratin 19-positive hepatocellular carcinoma.
Sign Up to like & getrecommendations! Published in 2018 at "Oncology letters"
DOI: 10.3892/ol.2017.7320
Abstract: A previous study demonstrated that cytokeratin 19 (CK19) expression in hepatocellular carcinoma (HCC) is an indicator of HCC invasiveness, including lymph node metastasis (LNM), tumor infiltration/non-encapsulation and poor prognosis. The exact mechanism by which CK19… read more here.
Keywords: hcc; poor prognosis; ck19; cdh17 ... See more keywords