DKK3/CKAP4 axis is associated with advanced stage and poorer prognosis in oral cancer.
Sign Up to like & getrecommendations! Published in 2022 at "Oral diseases"
DOI: 10.1111/odi.14277
Abstract: OBJECTIVE We previously reported that dickkopf WNT signaling inhibitor 3 (DKK3) would modulate malignant potential of Oral squamous cell carcinoma (OSCC) via activating Akt. Recently, cytoskeleton associated protein 4 (CKAP4) functions as receptor of DKK3,… read more here.
Keywords: ckap4 axis; dkk3 ckap4; stage; ckap4 ... See more keywords
CKAP4 Regulates Cell Migration via the Interaction with and Recycling of Integrin
Sign Up to like & getrecommendations! Published in 2019 at "Molecular and Cellular Biology"
DOI: 10.1128/mcb.00073-19
Abstract: Cytoskeleton-associated protein 4 (CKAP4) is an endoplasmic reticulum protein that is also present in the cell surface membrane, where it acts as a receptor for Dickkopf1 (DKK1). In this study, we found that CKAP4 interacts… read more here.
Keywords: cell migration; cell adhesion; ckap4; recycling integrin ... See more keywords
Expression of cytoskeleton-associated protein 4 is associated with poor prognosis and metastasis in nasopharyngeal carcinoma.
Sign Up to like & getrecommendations! Published in 2023 at "Experimental biology and medicine"
DOI: 10.1177/15353702231167940
Abstract: Cytoskeleton-associated protein 4 (CKAP4) acts as a key transmembrane protein that connects the endoplasmic reticulum (ER) to microtubule dynamics. Researchers have not examined the roles of CKAP4 in nasopharyngeal carcinoma (NPC). The study aimed at… read more here.
Keywords: metastasis; cytoskeleton associated; nasopharyngeal carcinoma; expression ... See more keywords
CKAP4 is a potential exosomal biomarker and therapeutic target for lung cancer
Sign Up to like & getrecommendations! Published in 2023 at "Translational Lung Cancer Research"
DOI: 10.21037/tlcr-22-571
Abstract: Background Globally, lung cancer causes the most cancer death. While molecular therapy progress, including epidermal growth factor receptor (EGFR) tyrosine kinase inhibitors (TKIs), has provided remarkable therapeutic effects, some patients remain resistant to these therapies… read more here.
Keywords: target lung; lung cancer; ckap4; cancer ... See more keywords
Cytoskeleton-associated protein 4 is a novel serodiagnostic marker for esophageal squamous-cell carcinoma
Sign Up to like & getrecommendations! Published in 2018 at "OncoTargets and therapy"
DOI: 10.2147/ott.s183790
Abstract: Background Recent years have witnessed significant progress in the treatment of esophageal squamous-cell carcinoma (ESCC); however, the prognosis of ESCC is still unsatisfactory. Bio-markers are required to improve identification of high-risk populations and help management… read more here.
Keywords: ckap4; serum ckap4; squamous cell; cell carcinoma ... See more keywords
Serum cytoskeleton-associated protein 4 as a biomarker for the diagnosis of hepatocellular carcinoma
Sign Up to like & getrecommendations! Published in 2019 at "OncoTargets and therapy"
DOI: 10.2147/ott.s189425
Abstract: Background Alpha-fetoprotein (AFP) is the most commonly applied biomarker for diagnosis of hepatocellular carcinoma (HCC), but the low sensitivity and specificity limit its clinical application. Cytoskeleton-associated protein 4 (CKAP4) is a novel oncogenic protein involved… read more here.
Keywords: hcc; biomarker; diagnosis hepatocellular; ckap4 ... See more keywords