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Published in 2017 at "Current Osteoporosis Reports"
DOI: 10.1007/s11914-017-0365-0
Abstract: Purpose of ReviewIn this paper, we review the pathogenesis and treatment of chronic kidney disease-mineral and bone disorder (CKD-MBD), especially as it relates to pediatric CKD patients.Recent FindingsDisordered regulation of bone and mineral metabolism in…
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Keywords:
ckd mbd;
treatment;
disorder;
disease ... See more keywords
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Published in 2017 at "Bone"
DOI: 10.1016/j.bone.2016.08.022
Abstract: Disordered calcium balance and homeostasis are common in patients with chronic kidney disease. Such alterations are commonly associated with abnormal bone remodeling, directly and indirectly. Similarly, positive calcium balance may also be a factor in…
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Keywords:
calcium;
ckd mbd;
calcium cardiovascular;
calcium balance ... See more keywords
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Published in 2018 at "Bone"
DOI: 10.1016/j.bone.2017.11.015
Abstract: Sclerostin is a soluble antagonist of canonical Wnt signaling and a strong inhibitor of bone formation. We present experimental data on the role of sclerostin in chronic kidney disease - bone mineral disorder (CKD-MBD). METHODS…
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Keywords:
ckd mbd;
bone;
sclerostin deficiency;
mice ... See more keywords
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Published in 2019 at "Kidney International Reports"
DOI: 10.1016/j.ekir.2019.09.007
Abstract: The Kidney Disease Improving Global Outcomes (KDIGO) Clinical Practice Guideline on Chronic Kidney Disease–Mineral and Bone Disorder (CKD–MBD) 2009 provided recommendations on the detection, evaluation, and treatment of CKD-MBD in patients CKD who are and…
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Keywords:
guideline;
ckd mbd;
kidney disease;
kidney ... See more keywords
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Published in 2021 at "Kidney International Reports"
DOI: 10.1016/j.ekir.2021.03.672
Abstract: Introduction: Chronic Kidney Disease related Mineral Bone Disease (CKD-MBD) can occur in all patients with CKD and leads to a variety of clinical manifestations, including bone pain and fractures characterized by abnormalities in the metabolism…
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Keywords:
patient;
ckd mbd;
calcium;
disease ... See more keywords
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Published in 2021 at "Kidney international"
DOI: 10.1016/j.kint.2021.05.024
Abstract: Patients with chronic kidney disease-mineral and bone disorder (CKD-MBD) frequently have low bone formation rates. A recent review suggested that adynamic bone disease is not always associated with negative outcomes and therefore antiresorptive medications could…
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Keywords:
patients ckd;
ckd mbd;
bone;
importance bone ... See more keywords
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Published in 2017 at "Nephrology"
DOI: 10.1111/nep.13022
Abstract: The revised Kidney Disease Improving Global Outcomes (KDIGO) guidelines for Chronic Kidney Disease Mineral and Bone Disorder (CKD-MBD) will soon be published. Perhaps the most important insight arising from the concept of CKD-MBD that was…
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Keywords:
bone;
ckd mbd;
disease;
kidney disease ... See more keywords
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Published in 2022 at "American Journal of Nephrology"
DOI: 10.1159/000521508
Abstract: Introduction: Chronic kidney disease-mineral and bone disorders (CKD-MBD) are prevalent in patients undergoing maintenance dialysis. Yet, there are limited and mixed evidence on the effects of different dialysis modalities involving longer treatment times or higher…
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Keywords:
center hemodialysis;
dialysis modalities;
ckd mbd;
dialysis ... See more keywords
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Published in 2019 at "Canadian Journal of Kidney Health and Disease"
DOI: 10.1177/2054358119870539
Abstract: Background: Recent studies have demonstrated that measurement of areal bone mineral density by dual-energy x-ray absorptiometry (DXA) predicts fractures in patients with chronic kidney disease (CKD). However, whether fracture risk prediction through bone mineral density…
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Keywords:
risk;
fracture;
ckd mbd;
disease ... See more keywords
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Published in 2017 at "PLoS ONE"
DOI: 10.1371/journal.pone.0168537
Abstract: The relationships between all-cause mortality and serum intact parathyroid hormone (iPTH), calcium, and phosphate are fairly diverse in patients on maintenance hemodialysis according to prior studies. This study evaluated the association of chronic kidney disease-mineral…
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Keywords:
hemodialysis;
mbd markers;
cause mortality;
ckd mbd ... See more keywords
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Published in 2018 at "PLoS ONE"
DOI: 10.1371/journal.pone.0205831
Abstract: Background Chronic kidney disease (CKD)-mineral and bone disorder (MBD) is a systemic disorder that leads to vascular calcification and accelerated atherosclerosis. Uric acid has been shown to associate with vascular calcification and with carotid intima-media…
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Keywords:
uric acid;
vascular calcification;
calcification;
ckd mbd ... See more keywords