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   Articles with "ckd mbd" as a keyword



Changes in bone density and microarchitecture in adolescents undergoing a first kidney transplantation: a prospective study

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recommendations! Published in 2024 at "European Journal of Pediatrics"

DOI: 10.1007/s00431-024-05777-z

Abstract: Mineral bone disorder associated with chronic kidney disease (CKD-MBD) frequently persists after kidney transplantation (KTx), being due to pre-existing CKD-MBD, immunosuppressive therapies, and post-KTx hypophosphatemia. This study aimed to evaluate bone biomarkers and microarchitecture using… read more here.

Keywords: disease; ckd mbd; ktx; bone ... See more keywords

Treatment of Pediatric Chronic Kidney Disease-Mineral and Bone Disorder

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recommendations! Published in 2017 at "Current Osteoporosis Reports"

DOI: 10.1007/s11914-017-0365-0

Abstract: Purpose of ReviewIn this paper, we review the pathogenesis and treatment of chronic kidney disease-mineral and bone disorder (CKD-MBD), especially as it relates to pediatric CKD patients.Recent FindingsDisordered regulation of bone and mineral metabolism in… read more here.

Keywords: ckd mbd; treatment; disorder; disease ... See more keywords

Calcium as a cardiovascular toxin in CKD-MBD.

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recommendations! Published in 2017 at "Bone"

DOI: 10.1016/j.bone.2016.08.022

Abstract: Disordered calcium balance and homeostasis are common in patients with chronic kidney disease. Such alterations are commonly associated with abnormal bone remodeling, directly and indirectly. Similarly, positive calcium balance may also be a factor in… read more here.

Keywords: calcium; ckd mbd; calcium cardiovascular; calcium balance ... See more keywords

Sclerostin deficiency modifies the development of CKD-MBD in mice.

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recommendations! Published in 2018 at "Bone"

DOI: 10.1016/j.bone.2017.11.015

Abstract: Sclerostin is a soluble antagonist of canonical Wnt signaling and a strong inhibitor of bone formation. We present experimental data on the role of sclerostin in chronic kidney disease - bone mineral disorder (CKD-MBD). METHODS… read more here.

Keywords: ckd mbd; bone; sclerostin deficiency; mice ... See more keywords

2017 Kidney Disease: Improving Global Outcomes (KDIGO) Chronic Kidney Disease–Mineral and Bone Disorder (CKD-MBD) Guideline Update Implementation: Asia Summit Conference Report

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recommendations! Published in 2019 at "Kidney International Reports"

DOI: 10.1016/j.ekir.2019.09.007

Abstract: The Kidney Disease Improving Global Outcomes (KDIGO) Clinical Practice Guideline on Chronic Kidney Disease–Mineral and Bone Disorder (CKD–MBD) 2009 provided recommendations on the detection, evaluation, and treatment of CKD-MBD in patients CKD who are and… read more here.

Keywords: guideline; ckd mbd; kidney disease; kidney ... See more keywords
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POS-642 MINERAL BONE DISEASE IN PATIENT CHRONIC KIDNEY DISEASE WITH CONTINUOUS AMBULATORY PERITONEAL DIALYSIS: A CASE REPORT

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recommendations! Published in 2021 at "Kidney International Reports"

DOI: 10.1016/j.ekir.2021.03.672

Abstract: Introduction: Chronic Kidney Disease related Mineral Bone Disease (CKD-MBD) can occur in all patients with CKD and leads to a variety of clinical manifestations, including bone pain and fractures characterized by abnormalities in the metabolism… read more here.

Keywords: patient; ckd mbd; calcium; disease ... See more keywords
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Importance of bone turnover for therapeutic decisions in patients with CKD-MBD.

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recommendations! Published in 2021 at "Kidney international"

DOI: 10.1016/j.kint.2021.05.024

Abstract: Patients with chronic kidney disease-mineral and bone disorder (CKD-MBD) frequently have low bone formation rates. A recent review suggested that adynamic bone disease is not always associated with negative outcomes and therefore antiresorptive medications could… read more here.

Keywords: patients ckd; ckd mbd; bone; importance bone ... See more keywords

#2215 Early molecular and cellular features of aortic remodeling in a mild CKD-MBD model with low bone turnover

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recommendations! Published in 2024 at "Nephrology Dialysis Transplantation"

DOI: 10.1093/ndt/gfae069.486

Abstract: Vascular calcification associated with a maladaptive bone response is common in CKD and is a major cause of mortality (up to 60% depending on CKD stage). Alterations in several intracellular signaling pathways have been reported… read more here.

Keywords: bone; aortic remodeling; bone turnover; ckd mbd ... See more keywords

#1891 Causal assessment of CKD-MBD phenotypes and CKD progression through a g-formula analysis—insights from the EQUAL study

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recommendations! Published in 2025 at "Nephrology Dialysis Transplantation"

DOI: 10.1093/ndt/gfaf116.0401

Abstract: Chronic Kidney Disease—Mineral and Bone Disorder (CKD-MBD) may both be a cause and a consequence of CKD progression. In the present study, we aim to assess the individual and combined causal effect of longitudinal CKD-MBD… read more here.

Keywords: ckd; ckd progression; ckd mbd; progression ... See more keywords

#2558 Dysregulation in Slc20a1/Slc20a2 associated with myocardial-bone axis in mild chronic kidney disease—mineral and bone disorder: experimental study

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recommendations! Published in 2025 at "Nephrology Dialysis Transplantation"

DOI: 10.1093/ndt/gfaf116.0417

Abstract: As we have previously shown, inorganic phosphate (Pi) retention and reduced bone formation occur concurrently with myocardial remodeling in a mild CKD-MBD model. This prompts further investigation into the molecular basis of the identified bone… read more here.

Keywords: ckd; slc20a2; ckd mbd; pit2 ... See more keywords

#2063 Association between CKD–MBD and mortality, cardiovascular events, and fractures in peritoneal dialysis patients

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recommendations! Published in 2025 at "Nephrology Dialysis Transplantation"

DOI: 10.1093/ndt/gfaf116.1756

Abstract: This observational study aimed to investigate the association between changes in chronic kidney disease-mineral and bone disorder (CKD-MBD)parameters and clinical outcomes in patients undergoing peritoneal dialysis (PD). It is well-established that abnormalities in CKD–MBD parameters… read more here.

Keywords: mbd parameters; risk; cardiovascular events; ckd mbd ... See more keywords