The HIF‐PHI BAY 85‐3934 (Molidustat) Improves Anemia and Is Associated With Reduced Levels of Circulating FGF23 in a CKD Mouse Model
Sign Up to like & getrecommendations! Published in 2021 at "Journal of Bone and Mineral Research"
DOI: 10.1002/jbmr.4272
Abstract: Fibroblast growth factor‐23 (FGF23) is a critical factor in chronic kidney disease (CKD), with elevated levels causing alterations in mineral metabolism and increased odds for mortality. Patients with CKD develop anemia as the kidneys progressively… read more here.
Keywords: bay; hif phi; ckd mice; ckd ... See more keywords
The association of cognition with protein energy wasting and synaptic transmission in chronic kidney disease.
Sign Up to like & getrecommendations! Published in 2023 at "Seminars in dialysis"
DOI: 10.1111/sdi.13146
Abstract: INTRODUCTION In recent years, consciousness impairment in patients with end-stage renal disease (ESRD) has been paid more and more attention, but the cause and mechanism of consciousness state change is not clear. METHODS As the… read more here.
Keywords: ckd mice; cognition; disease; protein energy ... See more keywords
Uremic Myopathy and Mitochondrial Dysfunction in Kidney Disease
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DOI: 10.3390/ijms232113515
Abstract: Alterations in muscle structure and function in chronic kidney disease (CKD) patients are associated with poor outcomes. As key organelles in muscle cell homeostasis, mitochondrial metabolism has been studied in the context of muscle dysfunction… read more here.
Keywords: ckd mice; uremic myopathy; muscle; ckd ... See more keywords
Growth Hormone Improves Adipose Tissue Browning and Muscle Wasting in Mice with Chronic Kidney Disease-Associated Cachexia
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DOI: 10.3390/ijms232315310
Abstract: Cachexia associated with chronic kidney disease (CKD) has been linked to GH resistance. In CKD, GH treatment enhances muscular performance. We investigated the impact of GH on cachexia brought on by CKD. CKD was induced… read more here.
Keywords: ckd; adipose tissue; muscle; ckd mice ... See more keywords