The HIF‐PHI BAY 85‐3934 (Molidustat) Improves Anemia and Is Associated With Reduced Levels of Circulating FGF23 in a CKD Mouse Model
Sign Up to like & getrecommendations! Published in 2021 at "Journal of Bone and Mineral Research"
DOI: 10.1002/jbmr.4272
Abstract: Fibroblast growth factor‐23 (FGF23) is a critical factor in chronic kidney disease (CKD), with elevated levels causing alterations in mineral metabolism and increased odds for mortality. Patients with CKD develop anemia as the kidneys progressively… read more here.
Keywords: bay; hif phi; ckd mice; ckd ... See more keywords
#539 The active ingredient in the Nuphar lutea plant DTBN, ameliorates kidney damage and inflammation in a mouse model of chronic kidney disease (CKD)
Sign Up to like & getrecommendations! Published in 2024 at "Nephrology Dialysis Transplantation"
DOI: 10.1093/ndt/gfae069.1353
Abstract: Complications associated with Chronic Kidney Disease (CKD), such as disease progression and anemia, are closely linked to heightened inflammation mediated by the innate immune response. This inflammation can be mitigated through the use of anti-inflammatory… read more here.
Keywords: ckd; mice; ckd mice; dtbn ... See more keywords
The association of cognition with protein energy wasting and synaptic transmission in chronic kidney disease.
Sign Up to like & getrecommendations! Published in 2023 at "Seminars in dialysis"
DOI: 10.1111/sdi.13146
Abstract: INTRODUCTION In recent years, consciousness impairment in patients with end-stage renal disease (ESRD) has been paid more and more attention, but the cause and mechanism of consciousness state change is not clear. METHODS As the… read more here.
Keywords: ckd mice; cognition; disease; protein energy ... See more keywords
Abstract Tu0092: Inflammation Plays a Pivotal Role in Uremia Driven Atherosclerosis Progression by Activating NLR Family Pyrin Domain Containing 3 (NLRP3) Inflammasome in Ldlr KO Mice
Sign Up to like & getrecommendations! Published in 2025 at "Arteriosclerosis, Thrombosis, and Vascular Biology"
DOI: 10.1161/atv.45.suppl_1.tu0092
Abstract: Atherosclerosis is highly prevalent in patients with chronic kidney disease (CKD). Cardiovascular mortality is 10 to 20 times higher in CKD patients than the general population. One clinical study also revealed an independent, graded association… read more here.
Keywords: ckd; mice; ckd mice; progression ... See more keywords
Abstract Mo060: SPEG mediates increased atrial fibrillation incidence in chronic kidney disease
Sign Up to like & getrecommendations! Published in 2024 at "Circulation Research"
DOI: 10.1161/res.135.suppl_1.mo060
Abstract: Introduction: Chronic kidney disease (CKD) is a major public health problem. CKD is a risk factor of cardiovascular morbidity and mortality due to the increased incidence of atrial fibrillation (AF). AF onset is known to… read more here.
Keywords: ckd; mice; speg; ckd mice ... See more keywords
Uremic Myopathy and Mitochondrial Dysfunction in Kidney Disease
Sign Up to like & getrecommendations! Published in 2022 at "International Journal of Molecular Sciences"
DOI: 10.3390/ijms232113515
Abstract: Alterations in muscle structure and function in chronic kidney disease (CKD) patients are associated with poor outcomes. As key organelles in muscle cell homeostasis, mitochondrial metabolism has been studied in the context of muscle dysfunction… read more here.
Keywords: ckd mice; uremic myopathy; muscle; ckd ... See more keywords
Growth Hormone Improves Adipose Tissue Browning and Muscle Wasting in Mice with Chronic Kidney Disease-Associated Cachexia
Sign Up to like & getrecommendations! Published in 2022 at "International Journal of Molecular Sciences"
DOI: 10.3390/ijms232315310
Abstract: Cachexia associated with chronic kidney disease (CKD) has been linked to GH resistance. In CKD, GH treatment enhances muscular performance. We investigated the impact of GH on cachexia brought on by CKD. CKD was induced… read more here.
Keywords: ckd; adipose tissue; muscle; ckd mice ... See more keywords