Computational Drug Screening Identifies Compounds Targeting Renal Age-associated Molecular Profiles
Sign Up to like & getrecommendations! Published in 2019 at "Computational and Structural Biotechnology Journal"
DOI: 10.1016/j.csbj.2019.06.019
Abstract: Aging is a major driver for chronic kidney disease (CKD) and the counterbalancing of aging processes holds promise to positively impact disease development and progression. In this study we generated a signature of renal age-associated… read more here.
Keywords: renal age; age associated; ckd; ckd progression ... See more keywords
Association of overhydration and serum pigment epithelium-derived factor with CKD progression in diabetic kidney disease: A prospective cohort study.
Sign Up to like & getrecommendations! Published in 2021 at "Diabetes research and clinical practice"
DOI: 10.1016/j.diabres.2021.108754
Abstract: AIM Little is known about whether overhydration (OH), measured using bioimpedance assay (BIA), is associated with CKD progression in patients with type 2 diabetes mellitus (T2DM). We hypothesised that OH was a predictor, and pigment… read more here.
Keywords: progression; factor ckd; pigment epithelium; ckd progression ... See more keywords
Low levels of urinary epidermal growth factor predict chronic kidney disease progression in children.
Sign Up to like & getrecommendations! Published in 2019 at "Kidney international"
DOI: 10.1016/j.kint.2019.01.035
Abstract: Urinary epidermal growth factor (uEGF) has recently been identified as a promising biomarker of chronic kidney disease (CKD) progression in adults with glomerular disease. Low levels of uEGF predict CKD progression and appear to reflect… read more here.
Keywords: progression; kidney disease; ckd progression;
MO478FACTORS ASSOCIATED IN RAPID PROGRESSION OF CHRONIC KIDNEY DISEASE: A MULTICENTRE, RETROSPECTIVE COHORT STUDY
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DOI: 10.1093/ndt/gfab090.0040
Abstract: Identification of risk factors linked with rapid chronic kidney disease (CKD) progression is beneficial in shaping preventative and management strategies for maximal benefits out of the existing resources and capacity of care. To this end,… read more here.
Keywords: ckd progression; progression; nephrology; ckd ... See more keywords
MO1049PROGRESSION OF CHRONIC KIDNEY DISEASE AND LONG-TERM MORTALITY IN PATIENTS HOSPITALIZED WITH TRICUSPID REGURGITATION
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DOI: 10.1093/ndt/gfab113.005
Abstract: Uremic toxins negatively affect the cardiovascular system resulting in significant morbidity and mortality. However, independent risk factors for chronic kidney disease (CKD) and that of worsening CKD have not been studied in patients with tricuspid… read more here.
Keywords: mortality; year mortality; ckd progression; progression ... See more keywords
FC 041TUBULAR EPITHELIAL CELL POLYPLOIDY IS ESSENTIAL TO SURVIVE AKI BUT IT CONTRIBUTES TO CKD PROGRESSION
Sign Up to like & getrecommendations! Published in 2021 at "Nephrology Dialysis Transplantation"
DOI: 10.1093/ndt/gfab119.001
Abstract: Acute Kidney Injury (AKI) is a syndrome characterized by an acute deterioration of renal function. Due to its high prevalence and poor short-term outcomes, AKI represents a global healthcare issue. Many epidemiologic studies have indicated… read more here.
Keywords: ckd progression; cell; polyploid cells; kidney ... See more keywords
Colchicine use and the risk of CKD progression: A multicenter nested case-control study.
Sign Up to like & getrecommendations! Published in 2022 at "Rheumatology"
DOI: 10.1093/rheumatology/keac077
Abstract: OBJECTIVES Despite the preclinical evidence on protective effects of colchicine against kidney fibrosis, whether colchicine could delay the progression of chronic kidney disease (CKD) in humans remains unknown. This study examined the association between long-term… read more here.
Keywords: kidney; progression; colchicine; risk ... See more keywords
Risk Factors for Progression of CKD with and without Diabetes
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DOI: 10.1155/2022/9613062
Abstract: Objective We aim to identify independent risk factors to predict CKD progression to end stage renal disease (ESRD) in patients with or without diabetes. Methods In this retrospective study, we enrolled CKD stage 3-4 patients… read more here.
Keywords: ckd; risk factors; without diabetes; ckd progression ... See more keywords
The Association of Sleep Duration and Quality with CKD Progression.
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DOI: 10.1681/asn.2016121288
Abstract: Evidence suggests that sleep disorders are common in individuals with CKD, but the influence of sleep duration and quality on CKD progression is unknown. We examined the association of habitual sleep duration and quality with… read more here.
Keywords: duration quality; ckd progression; duration; sleep duration ... See more keywords
Angiopoietins as Prognostic Markers for Future Kidney Disease and Heart Failure Events After Acute Kidney Injury.
Sign Up to like & getrecommendations! Published in 2022 at "Journal of the American Society of Nephrology : JASN"
DOI: 10.1681/asn.2021060757
Abstract: Background The mechanisms underlying long-term sequelae following acute kidney injury (AKI) remain unclear. Vessel instability, an early response to endothelial injury, may reflect a shared mechanism and early trigger for chronic kidney disease (CKD) and… read more here.
Keywords: ckd progression; angpt; heart; kidney ... See more keywords
The Impact of Carbamylation and Anemia on HbA1c’s Association With Renal Outcomes in Patients With Diabetes and Chronic Kidney Disease
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DOI: 10.2337/dc22-1399
Abstract: OBJECTIVE Glycated hemoglobin (HbA1c) can predict risk for microvascular complications in patients with diabetes. However, HbA1c’s reliability in chronic kidney disease (CKD) has been questioned, with concerns including competition from another posttranslational protein modification, carbamylation,… read more here.
Keywords: hba1c; carbamylation; anemia; ckd progression ... See more keywords