Studies on enmetazobactam clarify mechanisms of widely used β-lactamase inhibitors
Sign Up to like & getrecommendations! Published in 2022 at "Proceedings of the National Academy of Sciences of the United States of America"
DOI: 10.1073/pnas.2117310119
Abstract: Significance Microbial resistance to β-lactam antibiotics mediated by β-lactamase–catalyzed hydrolysis is a major global health concern. Penam sulfones, which are structurally related to penicillins, inhibit clinically important serine β-lactamases (SBLs) by forming transiently stable covalent… read more here.
Keywords: clarify mechanisms; studies enmetazobactam; enmetazobactam clarify; widely used ... See more keywords