CLASP2 facilitates dynamic actin filament organization along the microtubule lattice
Sign Up to like & getrecommendations! Published in 2022 at "Molecular Biology of the Cell"
DOI: 10.1091/mbc.e22-05-0149
Abstract: Coordination between the microtubule and actin networks is essential for cell motility, neuronal growth cone guidance, and wound healing. Members of the CLASP (Cytoplasmic Linker-Associated Protein) family of proteins have been implicated in the cytoskeletal… read more here.
Keywords: microtubule lattice; actin; clasp2; microtubule ... See more keywords
CLASP2 is involved in the EMT and early progression after transurethral resection of the bladder tumor
Sign Up to like & getrecommendations! Published in 2017 at "BMC Cancer"
DOI: 10.1186/s12885-017-3101-3
Abstract: BackgroundCytoplasmic linker-associated protein 2 (CLASP2) belongs to a family of microtubule plus-end tracking proteins that localizes to the distal ends of microtubules and regulate microtubule dynamics. We speculated that it might be involved in the… read more here.
Keywords: resection bladder; transurethral resection; clasp2; progression ... See more keywords
Clasp2 ensures mitotic fidelity and prevents differentiation of epidermal keratinocytes
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DOI: 10.1242/jcs.194787
Abstract: ABSTRACT Epidermal homeostasis is tightly controlled by a balancing act of self-renewal or terminal differentiation of proliferating basal keratinocytes. An increase in DNA content as a consequence of a mitotic block is a recognized mechanism… read more here.
Keywords: ensures mitotic; mitotic fidelity; clasp2; differentiation ... See more keywords
1779-P: Characterization of Insulin-Regulated CLASP2 Phosphorylation
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DOI: 10.2337/db19-1779-p
Abstract: During an unbiased proteomics screen of rat L6 myotubes, we previously discovered the first member of the microtubule plus-end interacting protein (+TIP) family that undergoes insulin-stimulated phosphorylation, CLIP-associating protein 2 (CLASP2). Here we report that… read more here.
Keywords: insulin stimulated; phosphorylation; clasp2 phosphorylation; clasp2 protein ... See more keywords