Discovery and Development of First-in-Class ACKR3/CXCR7 Superagonists for Platelet Degranulation Modulation.
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DOI: 10.1021/acs.jmedchem.2c01198
Abstract: The atypical chemokine receptor 3 (ACKR3), formerly known as CXC-chemokine receptor 7 (CXCR7), has been postulated to regulate platelet function and thrombus formation. Herein, we report the discovery and development of first-in-class ACKR3 agonists, which… read more here.
Keywords: discovery development; platelet degranulation; cxcr7; first class ... See more keywords