Synthesis and antibacterial evaluation of 13-substituted cycloberberine derivatives as a novel class of anti-MRSA agents.
Sign Up to like & getrecommendations! Published in 2018 at "European journal of medicinal chemistry"
DOI: 10.1016/j.ejmech.2018.08.050
Abstract: A series of new 13-substituted cycloberberine (CBBR) derivatives were prepared and evaluated for their antibacterial activities against Gram-positive bacteria taking CBBR as the lead. Structure-activity relationship revealed that the introduction of a suitable electron-donating group… read more here.
Keywords: substituted cycloberberine; anti mrsa; derivatives novel; mrsa agents ... See more keywords
Vesiculopolins, a New Class of Anti-Vesiculoviral Compounds, Inhibit Transcription Initiation of Vesiculoviruses
Sign Up to like & getrecommendations! Published in 2019 at "Viruses"
DOI: 10.3390/v11090856
Abstract: Vesicular stomatitis virus (VSV) represents a promising platform for developing oncolytic viruses, as well as vaccines against significant human pathogens. To safely control VSV infection in humans, small-molecule drugs that selectively inhibit VSV infection may… read more here.
Keywords: new class; vesiculopolins new; initiation; vesiculoviral compounds ... See more keywords