HLA class II antigen-processing pathway in tumors: Molecular defects and clinical relevance
Sign Up to like & getrecommendations! Published in 2017 at "OncoImmunology"
DOI: 10.1080/2162402x.2016.1171447
Abstract: ABSTRACT The human leukocyte antigen (HLA) class II antigen-processing machinery (APM) presents to cognate CD4+ T-cells antigenic peptides mainly generated from exogeneous proteins in the endocytic compartment. These CD4+ T cells exert helper function, but… read more here.
Keywords: class; antigen processing; class antigen; hla class ... See more keywords
HLA Class II Antigen Processing and Presentation Pathway Components Demonstrated by Transcriptome and Protein Analyses of Islet β-Cells From Donors With Type 1 Diabetes
Sign Up to like & getrecommendations! Published in 2019 at "Diabetes"
DOI: 10.2337/db18-0686
Abstract: Type 1 diabetes studies consistently generate data showing islet β-cell dysfunction and T cell–mediated anti-β-cell–specific autoimmunity. To explore the pathogenesis, we interrogated the β-cell transcriptomes from donors with and without type 1 diabetes using both… read more here.
Keywords: protein; donors type; class; type diabetes ... See more keywords