Abstract P5-05-05: Suppression of FOXM1 activities and breast cancer growth in vitro and in vivo by a new class of compounds
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DOI: 10.1158/1538-7445.sabcs19-p5-05-05
Abstract: The transcription factor FOXM1 is up-regulated and overexpressed in aggressive, therapy-resistant forms of hormone receptor-positive and triple negative breast cancers, and is associated with less good patient survival. FOXM1 signaling is also a key driver… read more here.
Keywords: new class; foxm1; class compounds; breast cancer ... See more keywords
1,2-Diarylethanols—A New Class of Compounds That Are Toxic to E. coli K12, R2–R4 Strains
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DOI: 10.3390/ma14041025
Abstract: An initial study of 1,2-diarylethanols derivatives as new potential antibacterial drugs candidates was conducted. Particular emphasis was placed on the selection of the structure of 1,2-diarylethanols with the highest biological activity of lipopolysaccharides (LPS) in… read more here.
Keywords: new class; class compounds; coli k12; compounds toxic ... See more keywords
δ-Lactones—A New Class of Compounds That Are Toxic to E. coli K12 and R2–R4 Strains
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DOI: 10.3390/ma14112956
Abstract: Lactones are among the well-known organic substances with a specific taste and smell. They are characterized by antibacterial, antiviral, anti-inflammatory, and anti-cancer properties. In recent years, among this group of compounds, new biologically active substances… read more here.
Keywords: new class; coli k12; class compounds; lactones new ... See more keywords