MHC class I diversity in chimpanzees and bonobos
Sign Up to like & getrecommendations! Published in 2017 at "Immunogenetics"
DOI: 10.1007/s00251-017-0990-x
Abstract: Major histocompatibility complex (MHC) class I genes are critically involved in the defense against intracellular pathogens. MHC diversity comparisons among samples of closely related taxa may reveal traces of past or ongoing selective processes. The… read more here.
Keywords: class diversity; diversity chimpanzees; class; central chimpanzees ... See more keywords
Uncovering the underlying physical mechanism for cancer-immunity of MHC class I diversity.
Sign Up to like & getrecommendations! Published in 2018 at "Biochemical and biophysical research communications"
DOI: 10.1016/j.bbrc.2018.08.170
Abstract: The cancer cells are heterogeneous populated, which can be classified as MHC class I positive and MHC I class negative. They influence the immune system differently. In this work, we build a core cancer-immune circuit… read more here.
Keywords: topography; class diversity; cancer; mechanism cancer ... See more keywords