On a Class of Dual Rickart Modules
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DOI: 10.1007/s11253-020-01847-1
Abstract: Let R be a ring and let ΩR be the set of maximal right ideals of R. An R-module M is called an sd-Rickart module if, for every nonzero endomorphism f of M, Imf is… read more here.
Keywords: class dual; rickart; rickart modules; dual rickart ... See more keywords
Design of First-in-Class Dual EZH2/HDAC Inhibitor: Biochemical Activity and Biological Evaluation in Cancer Cells.
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DOI: 10.1021/acsmedchemlett.0c00014
Abstract: Since the histone modifying enzymes EZH2 and HDACs control a number of epigenetic-dependent carcinogenic pathways, we designed the first-in-class dual EZH2/HDAC inhibitor 5 displaying (sub)micromolar inhibition against both targets. When tested in several cancer cell… read more here.
Keywords: class dual; dual ezh2; ezh2 hdac; hdac inhibitor ... See more keywords