Articles with "class expression" as a keyword



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P132 Differential HLA-C expression in caucasians: Useful data from direct HLA-protein measurements in 188 healthy German donors

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Published in 2017 at "Human Immunology"

DOI: 10.1016/j.humimm.2017.06.192

Abstract: Aim The established variability of HLA-C expression on cell surface, although already investigated in African Americans by Apps et al. Science 2013(1), has not been yet accordingly researched in Caucasians. Furthermore, the possibility that HLA-C… read more here.

Keywords: class expression; hla expression; hla class; hla ... See more keywords
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Abstract B041: AR suppresses MHC Class I expression and T-cell response in prostate cancer

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Published in 2023 at "Cancer Research"

DOI: 10.1158/1538-7445.prca2023-b041

Abstract: Immunotherapy is a treatment option that has had limited success with prostate cancer patients. The major histocompatibility complex (MHC) Class I plays a pivotal role in the adaptive immune response by presenting neo-antigens on the… read more here.

Keywords: class; prostate cancer; mhc class; class expression ... See more keywords
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MHC class II expression and potential antigen-presenting cells in the retina during experimental autoimmune uveitis

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Published in 2017 at "Journal of Neuroinflammation"

DOI: 10.1186/s12974-017-0915-5

Abstract: BackgroundControversy exists regarding which cell types are responsible for autoantigen presentation in the retina during experimental autoimmune uveitis (EAU) development. In this study, we aimed to identify and characterize the retinal resident and infiltrating cells… read more here.

Keywords: class; class expression; cell; mhc class ... See more keywords
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Loss of BAP1 Is Associated with Upregulation of the NFkB Pathway and Increased HLA Class I Expression in Uveal Melanoma

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Published in 2019 at "Cancers"

DOI: 10.3390/cancers11081102

Abstract: One of the characteristics of prognostically infaust uveal melanoma (UM) is an inflammatory phenotype, which is characterized by high numbers of infiltrating T cells and macrophages, and a high HLA Class I expression. We wondered… read more here.

Keywords: class expression; hla class; uveal melanoma; nfkb pathway ... See more keywords
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Stemness Correlates Inversely with MHC Class I Expression in Pediatric Small Round Blue Cell Tumors

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Published in 2022 at "Cancers"

DOI: 10.3390/cancers14153584

Abstract: Simple Summary Tumors occurring at a young age are distinct from tumors in older individuals, clinically and pathologically. As small round blue cell tumors (SRBCTs), they often show a resemblance to stem cells and immature… read more here.

Keywords: cell; mhc class; class; class expression ... See more keywords
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Down-Regulation of MHC Class I Expression in Human Keratinocytes Using Viral Vectors Containing US11 Gene of Human Cytomegalovirus and Cultivation on Bovine Collagen-Elastin Matrix (Matriderm®): Potential Approach for an Immune-Privileged Skin Substitute

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Published in 2019 at "International Journal of Molecular Sciences"

DOI: 10.3390/ijms20092056

Abstract: Skin transplantation, especially in burn patients, is still challenging because surgeons are faced with limited disposability of autologous donor side material. The in vitro culture of keratinocytes has become an important reconstructive option. However, only… read more here.

Keywords: viral vectors; class expression; class; gene ... See more keywords
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Effects of irradiation on human leukocyte antigen class I expression in human papillomavirus positive and negative base of tongue and mobile tongue squamous cell carcinoma cell lines.

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Published in 2017 at "International journal of oncology"

DOI: 10.3892/ijo.2017.3916

Abstract: Human papillomavirus (HPV) infection is a risk factor for oropharyngeal cancer, besides smoking and alcohol. Patients with HPV-positive tumors have a better prognosis than those with HPV-negative tumors. Furthermore, patients with HPV-positive tumors, with high… read more here.

Keywords: class expression; cell; expression; upci scc ... See more keywords
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IL-2 enhanced MHC class I expression in papillary thyroid cancer with Hashimoto's thyroiditis overcomes immune escape in vitro

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Published in 2020 at "Journal of Cancer"

DOI: 10.7150/jca.38330

Abstract: The impact of Hashimoto's thyroiditis (HT) on the progression of papillary thyroid cancer (PTC) is still unclear. Interleukin-2 (IL-2) is a growth factor and crucial for HT development. This study aimed at investigating the effect… read more here.

Keywords: class expression; ptc cells; ptc tissues; expression ... See more keywords