Distinct evolutionary trajectories of MHC class I and class II genes in Old World finches and buntings.
Sign Up to like & getrecommendations! Published in 2021 at "Heredity"
DOI: 10.1038/s41437-021-00427-8
Abstract: Major histocompatibility complex (MHC) genes code for key proteins of the adaptive immune system, which present antigens from intra-cellular (MHC class I) and extra-cellular (MHC class II) pathogens. Because of their unprecedented diversity, MHC genes… read more here.
Keywords: evolution; class; class genes; mhc class ... See more keywords
A long-range cis-regulatory element for class I odorant receptor genes
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DOI: 10.1038/s41467-017-00870-4
Abstract: Individual olfactory sensory neurons express a single odorant receptor gene from either class I genes residing in a single cluster on a single chromosome or class II genes spread over multiple clusters on multiple chromosomes.… read more here.
Keywords: class; class genes; odorant receptor; long range ... See more keywords
Widespread non‐coding polymorphism in HLA class II genes of International HLA and Immunogenetics Workshop cell lines
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DOI: 10.1111/tan.14571
Abstract: As the primary genetic determinant of immune recognition of self and non‐self, the hyperpolymorphic HLA genes play key roles in disease association and transplantation. The large, variably sized HLA class II genes have historically been… read more here.
Keywords: hla class; hla; class genes; immunogenetics ... See more keywords