Lineage-Specific Class-A GPCR Dynamics Reflect Diverse Chemosensory Adaptations in Lophotrochozoa
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DOI: 10.1093/molbev/msaf042
Abstract: Abstract Sensing external chemosensory cues via Class-A G protein-coupled receptors (GPCRs) is crucial for a multitude of behavioral and biological functions, influencing animal evolution and ecological adaptations. While extensively studied in vertebrates and echinoderms, the… read more here.
Keywords: specific expansions; lineage; class gpcr; lineage specific ... See more keywords
Progress on the development of Class A GPCR‐biased ligands
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DOI: 10.1111/bph.17301
Abstract: Class A G protein‐coupled receptors (GPCRs) continue to garner interest for their essential roles in cell signalling and their importance as drug targets. Although numerous drugs in the clinic target these receptors, over 60% GPCRs… read more here.
Keywords: progress development; class; development class; class gpcr ... See more keywords