Identification of the Catalytic Residues in the Cyclase Domain of the Class IV Lanthipeptide Synthetase SgbL
Sign Up to like & getrecommendations! Published in 2021 at "ChemBioChem"
DOI: 10.1002/cbic.202100391
Abstract: Lanthipeptides belong to the family of ribosomally synthesized and post‐translationally modified peptides (RiPPs) and are subdivided into different classes based on their processing enzymes. The three‐domain class IV lanthipeptide synthetases (LanL enzymes) consist of N‐terminal… read more here.
Keywords: catalytic residues; residues cyclase; domain class; class lanthipeptide ... See more keywords
Lanthipeptides from the Same Core Sequence: Characterization of a Class II Lanthipeptide Synthetase from Microcystis aeruginosa NIES-88.
Sign Up to like & getrecommendations! Published in 2022 at "Organic letters"
DOI: 10.1021/acs.orglett.2c00573
Abstract: Class II lanthipeptide synthetases (LanMs) are relatively promiscuous to core peptide variations. Previous studies have shown that different LanMs catalyze identical reactions on the same core sequence fused to their respective cognate leaders. We characterized… read more here.
Keywords: core sequence; class lanthipeptide; microcystis aeruginosa; aeruginosa nies ... See more keywords