Articles with "class old" as a keyword



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Structural characterization of Class 2 OLD family nucleases supports a two-metal catalysis mechanism for cleavage

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Published in 2019 at "Nucleic Acids Research"

DOI: 10.1093/nar/gkz703

Abstract: Abstract Overcoming lysogenization defect (OLD) proteins constitute a family of uncharacterized nucleases present in bacteria, archaea, and some viruses. These enzymes contain an N-terminal ATPase domain and a C-terminal Toprim domain common amongst replication, recombination,… read more here.

Keywords: mechanism; class old; two metal; family ... See more keywords