Cooperativity of hydrogen bonding network in microsolvated biotin, the ligand of avidin class proteins
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DOI: 10.1007/s00894-019-4253-7
Abstract: Biotin is well known to be bound with exceptional strength by the avidin class of proteins. This ability comes from a match between the biotin-binding pocket of the protein and the structural elements of biotin,… read more here.
Keywords: class proteins; hydrogen; avidin class; hydrogen bonding ... See more keywords
In Silico-Based Structural Evaluation to Categorize the Pathogenicity of Mutations Identified in the RAD Class of Proteins
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DOI: 10.1021/acsomega.2c07802
Abstract: RAD genes, known as double-strand break repair proteins, play a major role in maintaining the genomic integrity of a cell by carrying out essential DNA repair functions via double-strand break repair pathways. Mutations in the… read more here.
Keywords: pathogenicity; rad class; mutations identified; class proteins ... See more keywords
The functional diversity of the POUV-class proteins across vertebrates
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DOI: 10.1098/rsob.220065
Abstract: POUV is a relatively newly emerged class of POU transcription factors present in jawed vertebrates (Gnathostomata). The function of POUV-class proteins is inextricably linked to zygotic genome activation (ZGA). A large body of evidence now… read more here.
Keywords: pouv class; class; class proteins; functional diversity ... See more keywords
Transmembrane Membrane Readers form a Novel Class of Proteins That Include Peripheral Phosphoinositide Recognition Domains and Viral Spikes
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DOI: 10.3390/membranes12111161
Abstract: Membrane proteins are broadly classified as transmembrane (TM) or peripheral, with functions that pertain to only a single bilayer at a given time. Here, we explicate a class of proteins that contain both transmembrane and… read more here.
Keywords: transmembrane peripheral; membrane readers; transmembrane membrane; membrane ... See more keywords