In silico analyses and experimental validation of the MHC class-I restricted epitopes of Ebolavirus GP.
Sign Up to like & getrecommendations! Published in 2022 at "International immunology"
DOI: 10.1093/intimm/dxac006
Abstract: Ebolavirus (EBOV) causes an extremely high mortality and prevalence disease called Ebola virus disease (EVD). There is only one glycoprotein (GP) on the virus particle surface, which mediates entry into the host cell. MHC class-I… read more here.
Keywords: class; restricted epitopes; class restricted; mhc class ... See more keywords
Evaluating the immunomodulatory responses of LdODC‐derived MHC Class‐II restricted peptides against VL
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DOI: 10.1111/pim.12699
Abstract: In a bid to develop a novel immunoprophylactic measure against visceral leishmaniasis (VL), MHC class‐II–restricted epitopes of LdODC were identified by reverse vaccinology approach. Five consensus HLA‐DRB1*0101‐restricted epitopes were screened. The analysis revealed that the… read more here.
Keywords: responses ldodc; evaluating immunomodulatory; class; immunomodulatory responses ... See more keywords
Identification of HLA class I-restricted immunogenic neoantigens in triple negative breast cancer
Sign Up to like & getrecommendations! Published in 2022 at "Frontiers in Immunology"
DOI: 10.3389/fimmu.2022.985886
Abstract: Immune checkpoint inhibitor (ICI)-based immunotherapy in triple negative breast cancer (TNBC) is achieving limited therapeutic results, requiring the development of more potent strategies. Combination of ICI with vaccination strategies would enhance antitumor immunity and response… read more here.
Keywords: hla class; triple negative; breast cancer; negative breast ... See more keywords