Spontaneous Formation of an Fe/Mn Diamond Core: Models for the Fe/Mn Sites in Class 1c Ribonucleotide Reductases.
Sign Up to like & getrecommendations! Published in 2021 at "Inorganic chemistry"
DOI: 10.1021/acs.inorgchem.1c00684
Abstract: A handful of oxygen-activating enzymes has recently been found to contain Fe/Mn active sites, like Class 1c ribonucleotide reductases and R2-like ligand-binding oxidase, which are closely related to their better characterized diiron cousins. These enzymes… read more here.
Keywords: ribonucleotide reductases; class ribonucleotide; diamond; diamond core ... See more keywords
Characterization of a second class Ie ribonucleotide reductase
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DOI: 10.1038/s42003-025-07565-3
Abstract: Class I ribonucleotide reductases (RNRs) convert ribonucleotides into deoxyribonucleotides under oxic conditions. The R2 subunit provides a radical required for catalysis conducted by the R1 subunit. In most R2s the radical is generated on a… read more here.
Keywords: characterization second; class ribonucleotide; class; ribonucleotide ... See more keywords
Structures of Class Id Ribonucleotide Reductase Catalytic Subunits Reveal a Minimal Architecture for Deoxynucleotide Biosynthesis.
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DOI: 10.2210/pdb6dqx/pdb
Abstract: Class I ribonucleotide reductases (RNRs) share a common mechanism of nucleotide reduction in a catalytic α subunit. All RNRs initiate catalysis with a thiyl radical, generated in class I enzymes by a metallocofactor in a… read more here.
Keywords: class; class ribonucleotide; structures class; rnrs ... See more keywords