Evaluation of Glycolytic Response to Multiple Classes of Anti-glioblastoma Drugs by Noninvasive Measurement of Pyruvate Kinase M2 Using [18F]DASA-23
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DOI: 10.1007/s11307-019-01353-2
Abstract: PurposePyruvate kinase M2 (PKM2) catalyzes the final step in glycolysis, the key process of tumor metabolism. PKM2 is found in high levels in glioblastoma (GBM) cells with marginal expression within healthy brain tissue, rendering it… read more here.
Keywords: classes anti; gbm; glycolytic response; dasa ... See more keywords