Unique Structural Platforms of Suz12 Dictate Distinct Classes of PRC2 for Chromatin Binding.
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DOI: 10.1016/j.molcel.2018.01.039
Abstract: Developmentally regulated accessory subunits dictate PRC2 function. Here, we report the crystal structures of a 120 kDa heterotetrameric complex consisting of Suz12, Rbbp4, Jarid2, and Aebp2 fragments that is minimally active in nucleosome binding and of… read more here.
Keywords: distinct classes; unique structural; suz12; classes prc2 ... See more keywords