GM-CSF production by non-classical monocytes controls antagonistic LPS-driven functions in allergic inflammation
Sign Up to like & getrecommendations! Published in 2021 at "Cell reports"
DOI: 10.1016/j.celrep.2021.110178
Abstract: SUMMARY Lipopolysaccharide (LPS) can either promote or prevent T helper 2 (Th2) cell allergic responses. However, the underlying mechanism remains unknown. We show here that LPS activity switches from pro-pathogenic to protective depending on the… read more here.
Keywords: csf production; classical monocytes; production non; non classical ... See more keywords
Characteristics of circulating monocytes at baseline and after activation in patients with intracranial aneurysm.
Sign Up to like & getrecommendations! Published in 2019 at "Human immunology"
DOI: 10.1016/j.humimm.2019.11.003
Abstract: Intracranial aneurysm (IA) is a bulging of blood vessels around the brain that is often asymptomatic but may cause severe complications and death if ruptured. Macrophage-mediated immune responses can contribute to the development of IA.… read more here.
Keywords: intracranial aneurysm; circulating monocytes; cd14 cd16; expression ... See more keywords
Integrin &agr;M&bgr;2 is differently expressed by subsets of human osteoclast precursors and mediates adhesion of classical monocytes to bone
Sign Up to like & getrecommendations! Published in 2017 at "Experimental Cell Research"
DOI: 10.1016/j.yexcr.2016.11.018
Abstract: Abstract Bone‐degrading osteoclasts are formed through fusion of their monocytic precursors. In the population of human peripheral blood monocytes, three distinct subsets have been identified: classical, intermediate and non‐classical monocytes. We have previously shown that… read more here.
Keywords: agr bgr; integrin agr; bone; osteoclast precursors ... See more keywords
Expression of VEGFA-mRNA in classical and MSX2-mRNA in non-classical monocytes in patients with spondyloarthritis is associated with peripheral arthritis
Sign Up to like & getrecommendations! Published in 2021 at "Scientific Reports"
DOI: 10.1038/s41598-021-89037-2
Abstract: Spondyloarthritis (SpA) is characterized by chronic inflammation and structural damage involving spine and peripheral joints. Monocytes, as part of innate immune system, following migration into affected tissue, may play a role in the pathogenesis of… read more here.
Keywords: peripheral arthritis; classical msx2; non classical; expression ... See more keywords
S100A9/CD163 expression profiles in classical monocytes as biomarkers to discriminate idiopathic pulmonary fibrosis from idiopathic nonspecific interstitial pneumonia
Sign Up to like & getrecommendations! Published in 2021 at "Scientific Reports"
DOI: 10.1038/s41598-021-91407-9
Abstract: Circulating monocytes have pathogenic relevance in idiopathic pulmonary fibrosis (IPF). Here, we determined whether the cell surface levels of two markers, pro-inflammatory-related S100A9 and anti-inflammatory-related CD163, expressed on CD14strongCD16− classical monocytes by flow cytometry could… read more here.
Keywords: s100a9 cd163; idiopathic pulmonary; cd163; pulmonary fibrosis ... See more keywords
Circulating classical monocytes are associated with CD11c+ macrophages in human visceral adipose tissue
Sign Up to like & getrecommendations! Published in 2017 at "Scientific Reports"
DOI: 10.1038/srep42665
Abstract: Immune cell accumulation in adipose tissue (AT) is associated with the development of AT inflammation, resulting in metabolic dysfunction. Circulating immune cell patterns may reflect immune cell accumulation in expanding AT. However, data linking human… read more here.
Keywords: immune cell; monocytes associated; associated cd11c; cd11c macrophages ... See more keywords
Recovery of systemic hyperinflammation in patients with severe SARS-CoV-2 infection
Sign Up to like & getrecommendations! Published in 2022 at "Biomarkers"
DOI: 10.1080/1354750x.2022.2148745
Abstract: Abstract Introduction Patients with cardiovascular disease (CVD) and acute SARS-CoV-2 infection might show an altered immune response during COVID-19. Material and methods Twenty-three patients with CVD and SARS-CoV-2 infection were prospectively enrolled and received a… read more here.
Keywords: acute sars; classical monocytes; cov infection; sars cov ... See more keywords
Immunoparalysis in critically ill children
Sign Up to like & getrecommendations! Published in 2022 at "Immunology"
DOI: 10.1111/imm.13595
Abstract: Immunoparalysis is associated with poorer outcomes in the paediatric intensive care unit (PICU) setting. We aimed to determine the group of patients with higher chances of immunoparalysis and correlate this status with increased risks of… read more here.
Keywords: frequency; immunoparalysis; classical monocytes; monocytes producing ... See more keywords
Non-classical monocyte homing to the gut via α4β7 integrin mediates macrophage-dependent intestinal wound healing
Sign Up to like & getrecommendations! Published in 2019 at "Gut"
DOI: 10.1136/gutjnl-2018-316772
Abstract: Objective To study the role of α4β7 integrin for gut homing of monocytes and to explore the biological consequences of therapeutic α4β7 inhibition with regard to intestinal wound healing. Design We studied the expression of… read more here.
Keywords: wound healing; integrin; non classical; intestinal wound ... See more keywords
Accumulation of classical monocytes defines a subgroup of MDS that frequently evolves into CMML.
Sign Up to like & getrecommendations! Published in 2017 at "Blood"
DOI: 10.1182/blood-2017-04-779579
Abstract: To the editor: Even though the diagnosis criteria of chronic myelomonocytic leukemia (CMML) have been recently revised by the World Health Organization (WHO),[1][1] recognition of this disease can be challenging. We demonstrated recently that a… read more here.
Keywords: mds frequently; monocytes defines; defines subgroup; subgroup mds ... See more keywords
Transcriptional profiling reveals functional dichotomy between human slan+ non‐classical monocytes and myeloid dendritic cells
Sign Up to like & getrecommendations! Published in 2017 at "Journal of Leukocyte Biology"
DOI: 10.1189/jlb.3ma0117-037r
Abstract: Human 6‐sulfo LacNac‐positive (slan+) cells have been subject to a paradigm debate. They have previously been classified as a distinct dendritic cell (DC) subset. However, evidence has emerged that they may be more related to… read more here.
Keywords: transcriptional profiling; slan; non classical; slan cells ... See more keywords