Articles with "classical non" as a keyword



MRI Is a DNA Damage Response Adaptor during Classical Non-homologous End Joining.

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Published in 2018 at "Molecular cell"

DOI: 10.1016/j.molcel.2018.06.018

Abstract: The modulator of retrovirus infection (MRI or CYREN) is a 30-kDa protein with a conserved N-terminal Ku-binding motif (KBM) and a C-terminal XLF-like motif (XLM). We show that MRI is intrinsically disordered and interacts with… read more here.

Keywords: end joining; dna damage; damage response; classical non ... See more keywords

Focus on the classical and non-classical functions of EZH2: Guide the development of inhibitors and degraders.

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Published in 2022 at "Pharmacological research"

DOI: 10.1016/j.phrs.2022.106159

Abstract: Enhancer of zeste homologue 2 (EZH2, also known as KMT6A) is found to be a member of the histone lysine methyltransferase family. An increasing number of studies have shown that in addition to methylating histones,… read more here.

Keywords: classical functions; focus classical; classical non; functions ezh2 ... See more keywords

Distinguishing and unraveling classical and non-classical pathways in MFI zeolite crystallization: Insights into their contributions and impact on the final product

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Published in 2025 at "Inorganic Chemistry Frontiers"

DOI: 10.1039/d5qi00224a

Abstract: Simplifying complex synthesis system containing multiple species into ones with single classical or nonclassical growth path is valuable for understanding their respective mechanisms. However, most zeolites growth involves intertwined classical... read more here.

Keywords: unraveling classical; non classical; classical non; pathways mfi ... See more keywords
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Revising CX3CR1 Expression on Murine Classical and Non-classical Monocytes

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Published in 2020 at "Frontiers in Immunology"

DOI: 10.3389/fimmu.2020.01117

Abstract: In mice, monocytes (Mo) are conventionally described as CX3CR1low classical Mo (CMo) and CX3CR1high non-classical Mo (NCMo) based on the expression of EGFP in Cx3cr1+/EGFP mice and by analogy with human CX3CR1 expression. Although this… read more here.

Keywords: classical non; cx3cr1; non classical; expression ... See more keywords

Myeloid antigen-presenting cells in neurodegenerative diseases: a focus on classical and non-classical MHC molecules

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Published in 2024 at "Frontiers in Neuroscience"

DOI: 10.3389/fnins.2024.1488382

Abstract: In recent years, increasing evidence has highlighted the critical role of myeloid cells, specifically those that present antigen (APCs) in health and disease. These shape the progression and development of neurodegenerative disorders, where considerable interplay… read more here.

Keywords: antigen; classical mhc; non classical; classical non ... See more keywords
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Mutational phospho-mimicry reveals a regulatory role for the XRCC4 and XLF C-terminal tails in modulating DNA bridging during classical non-homologous end joining

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Published in 2017 at "eLife"

DOI: 10.7554/elife.22900

Abstract: XRCC4 and DNA Ligase 4 (LIG4) form a tight complex that provides DNA ligase activity for classical non-homologous end joining (the predominant DNA double-strand break repair pathway in higher eukaryotes) and is stimulated by XLF.… read more here.

Keywords: dna; xlf; dna bridging; xrcc4 xlf ... See more keywords