A decade of using small-to-medium throughput allele discrimination assay to determine prion protein gene (Prnp) genotypes in sheep in Slovenia
Sign Up to like & getrecommendations! Published in 2018 at "Journal of Veterinary Diagnostic Investigation"
DOI: 10.1177/1040638717723946
Abstract: Sheep with valine (V) at codon 136 and glutamine (Q) at codon 171 of the prion protein gene (Prnp) are highly susceptible to classical scrapie, whereas phenylalanine (F) at codon 141 and histidine (H) at… read more here.
Keywords: small medium; scrapie; classical scrapie; prion protein ... See more keywords
Second passage of chronic wasting disease of mule deer to sheep by intracranial inoculation compared to classical scrapie
Sign Up to like & getrecommendations! Published in 2021 at "Journal of Veterinary Diagnostic Investigation"
DOI: 10.1177/10406387211017615
Abstract: The origin of chronic wasting disease (CWD) in cervids is unclear. One hypothesis suggests that CWD originated from scrapie in sheep. We compared the disease phenotype of sheep-adapted CWD to classical scrapie in sheep. We… read more here.
Keywords: cwd; scrapie; disease; classical scrapie ... See more keywords
Autoclave treatment of the classical scrapie agent US No. 13-7 and experimental inoculation to susceptible VRQ/ARQ sheep via the oral route results in decreased transmission efficiency
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DOI: 10.1371/journal.pone.0243009
Abstract: Scrapie, a prion disease of sheep, is highly resistant to conventional deactivation. Numerous methods to deactivate scrapie have been tested in laboratory animal models, and adequate autoclave treatment can reduce or remove the infectivity of… read more here.
Keywords: susceptible vrq; autoclave treatment; scrapie; classical scrapie ... See more keywords
Genetic resistance to transmissible spongiform encephalopathies (TSE) in goats
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DOI: 10.2903/j.efsa.2017.4962
Abstract: Abstract Breeding programmes to promote resistance to classical scrapie, similar to those for sheep in existing transmissible spongiform encephalopathies (TSE) regulations, have not been established in goats. The European Commission requested a scientific opinion from… read more here.
Keywords: classical scrapie; resistance; transmissible spongiform; genetic resistance ... See more keywords