Procerolides A-B from Microcionidae marine sponge Clathria procera: Anti-inflammatory macrocylic lactones with selective cyclooxygenase-2 attenuation properties.
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DOI: 10.1016/j.bioorg.2021.104663
Abstract: Cyclooxygenase-2 has been recognized to catalyze the formation of inflammatory prostaglandins from arachidonic acid. Attenuation potential against cyclooxygenase-2 coupled with greater anti-inflammatory selectivity index were contemplated to be vital indicators to assess anti-inflammatory activities of… read more here.
Keywords: anti inflammatory; cyclooxygenase; attenuation; marine sponge ... See more keywords