Clathrin-independent endocytosis: an increasing degree of complexity
Sign Up to like & getrecommendations! Published in 2018 at "Histochemistry and Cell Biology"
DOI: 10.1007/s00418-018-1678-5
Abstract: This article aims at providing an update on the complexity of clathrin-independent endocytosis. It is now almost 30Â years since we first wrote a review about its existence; at that time many people believed that with… read more here.
Keywords: clathrin independent; endocytosis; independent endocytosis; complexity clathrin ... See more keywords
Cellular uptake of extracellular vesicles is mediated by clathrinâindependent endocytosis and macropinocytosis
Sign Up to like & getrecommendations! Published in 2017 at "Journal of Controlled Release"
DOI: 10.1016/j.jconrel.2017.09.019
Abstract: ABSTRACT Recent evidence has established that extracellular vesicles (EVs), including exosomes and microvesicles, form an endogenous transport system through which biomolecules, including proteins and RNA, are exchanged between cells. This endows EVs with immense potential… read more here.
Keywords: clathrin independent; extracellular vesicles; independent endocytosis; endocytosis macropinocytosis ... See more keywords
Mechanisms of Carrier Formation during Clathrin-Independent Endocytosis.
Sign Up to like & getrecommendations! Published in 2018 at "Trends in cell biology"
DOI: 10.1016/j.tcb.2017.11.004
Abstract: Clathrin-independent endocytosis (CIE) mediates the cellular uptake of many extracellular ligands, receptors, and pathogens, including several life-threatening bacterial toxins and viruses. So far, our understanding of CIE carrier formation has lagged behind that of clathrin-coated… read more here.
Keywords: cie; carrier formation; independent endocytosis; endocytosis ... See more keywords
Myosin II isoforms promote internalization of spatially distinct clathrin-independent endocytosis cargoes through modulation of cortical tension downstream of ROCK2
Sign Up to like & getrecommendations! Published in 2020 at "Molecular Biology of the Cell"
DOI: 10.1091/mbc.e20-07-0480
Abstract: Although the actomyosin cytoskeleton has been implicated in clathrin-mediated endocytosis, a clear requirement for actomyosin in clathrin-independent endocytosis (CIE) has not been demonstrated. We discovered that the Rho-associated kinase ROCK2 is required for CIE of… read more here.
Keywords: myosin; internalization; clathrin independent; endocytosis ... See more keywords
Self-assembly and structure of a clathrin-independent AP-1:Arf1 tubular membrane coat
Sign Up to like & getrecommendations! Published in 2022 at "Science Advances"
DOI: 10.1101/2022.05.23.493093
Abstract: The AP adaptor complexes are best known for forming the inner layer of clathrin coats on spherical vesicles. AP complexes also have many clathrin-independent roles in tubulovesicular membrane traffic, whose structural and mechanistic basis has… read more here.
Keywords: structure; coat; arf1 tubular; membrane ... See more keywords
Rac1, actin cytoskeleton and microtubules are key players in clathrin-independent endophilin-A3-mediated endocytosis.
Sign Up to like & getrecommendations! Published in 2022 at "Journal of cell science"
DOI: 10.1242/jcs.259623
Abstract: Endocytic mechanisms actively regulate plasma membrane composition and sustain fundamental cellular functions. Recently, we identified a clathrin-independent endocytic (CIE) modality mediated by the BAR domain protein endophilin-A3 (endoA3), which controls the cell surface homeostasis of… read more here.
Keywords: actin cytoskeleton; rac1; cie; clathrin independent ... See more keywords