Unrecognized role of claudin‐10b in basolateral membrane infoldings of the thick ascending limb
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DOI: 10.1111/nyas.14882
Abstract: Claudin‐10b is an important component of the tight junction in the thick ascending limb (TAL) of Henle's loop and allows paracellular sodium transport. In immunofluorescence stainings, claudin‐10b–positive cells exhibited extensive extra staining of basolateral, column‐like… read more here.
Keywords: microscopy; ascending limb; thick ascending; claudin 10b ... See more keywords
Altered paracellular cation permeability due to a rare CLDN10B variant causes anhidrosis and kidney damage
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DOI: 10.1371/journal.pgen.1006897
Abstract: Claudins constitute the major component of tight junctions and regulate paracellular permeability of epithelia. Claudin-10 occurs in two major isoforms that form paracellular channels with ion selectivity. We report on two families segregating an autosomal… read more here.
Keywords: claudin; causes anhidrosis; permeability; 10b n48k ... See more keywords