Dichotomous roles of claudins as tumor promoters or suppressors: lessons from knockout mice
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DOI: 10.1007/s00018-019-03238-7
Abstract: Claudins are a family of integral tight junction proteins that regulate paracellular permeability in polarized epithelia. Overexpression or reduction of claudins can both promote and limit cancer progression, revealing complex dichotomous roles for claudins depending… read more here.
Keywords: knockout mice; cancer; roles claudins; dichotomous roles ... See more keywords