CLCA1 mediates the regulatory effect of IL-13 on pediatric asthma
Sign Up to like & getrecommendations! Published in 2022 at "Frontiers in Pediatrics"
DOI: 10.3389/fped.2022.959439
Abstract: Objective CLCA1 is a secreted protein with protease activity, and its expression is associated with inflammatory airway diseases. This study aimed to investigate the role of CLCA1 and IL-13 in pediatric asthma. Methods In asthmatic… read more here.
Keywords: effect; expression; clca1; activity ... See more keywords
CLCA1 Regulates Airway Mucus Production and Ion Secretion Through TMEM16A
Sign Up to like & getrecommendations! Published in 2021 at "International Journal of Molecular Sciences"
DOI: 10.3390/ijms22105133
Abstract: TMEM16A, a Ca2+-activated chloride channel (CaCC), and its regulator, CLCA1, are associated with inflammatory airway disease and goblet cell metaplasia. CLCA1 is a secreted protein with protease activity that was demonstrated to enhance membrane expression… read more here.
Keywords: secretion; mucus production; expression; tmem16a ... See more keywords