Clinical impact of baseline renal function on safety and early discontinuation of adjuvant capecitabine plus oxaliplatin in elderly patients with resected colon cancer: a multicenter post-marketing surveillance study.
Sign Up to like & getrecommendations! Published in 2019 at "Japanese journal of clinical oncology"
DOI: 10.1093/jjco/hyz149
Abstract: BACKGROUND Adjuvant capecitabine and oxaliplatin (CAPOX) is a standard treatment for resected colon cancer; however, in patients with moderate renal impairment, the incidence of CAPOX-related adverse events (AEs) and the rate of early discontinuation are… read more here.
Keywords: renal function; colon cancer; clcr; clcr group ... See more keywords
Creatinine Assessment in Non–Steady-State Conditions: A Critical Review
Sign Up to like & getrecommendations! Published in 2021 at "Annals of Pharmacotherapy"
DOI: 10.1177/1060028021999644
Abstract: Objectives: To discuss methods for the assessment of creatinine clearance (Clcr) when serum creatinine (SCr) is not at steady state in order to estimate kidney function and apply the estimate to kidney function staging for… read more here.
Keywords: state; creatinine; clcr; state conditions ... See more keywords