CLDN2 inhibits the metastasis of osteosarcoma cells via down-regulating the afadin/ERK signaling pathway
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DOI: 10.1186/s12935-018-0662-4
Abstract: BackgroundIn an earlier study, we investigated the expression of tight junction protein claudins (CLDNs) in human osteosarcoma (OS) cells, and the CLDN2 was found to be down-regulated in primary tumor cells compared with normal osteoblast cells. Here,… read more here.
Keywords: western blotting; expression; osteosarcoma cells; cldn2 ... See more keywords
Kaempferide Enhances Chemosensitivity of Human Lung Adenocarcinoma A549 Cells Mediated by the Decrease in Phosphorylation of Akt and Claudin-2 Expression
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DOI: 10.3390/nu12041190
Abstract: Claudins (CLDNs) play crucial roles in the formation of tight junctions. We have reported that abnormal expression of CLDN2 confers chemoresistance in the spheroids of human lung adenocarcinoma A549 cells. A food composition, which can… read more here.
Keywords: lung adenocarcinoma; a549 cells; expression; cldn2 ... See more keywords