Articles with "cldn3" as a keyword



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Development of Human Monoclonal Antibody for Claudin-3 Overexpressing Carcinoma Targeting

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Published in 2019 at "Biomolecules"

DOI: 10.3390/biom10010051

Abstract: Most malignant tumors originate from epithelial tissues in which tight junctions mediate cell–cell interactions. Tight junction proteins, especially claudin-3 (CLDN3), are overexpressed in various cancers. Claudin-3 is exposed externally during tumorigenesis making it a potential… read more here.

Keywords: development human; cldn3; carcinoma; monoclonal antibody ... See more keywords