Variants of human CLDN9 cause mild to profound hearing loss
Sign Up to like & getrecommendations! Published in 2021 at "Human Mutation"
DOI: 10.1002/humu.24260
Abstract: Hereditary deafness is clinically and genetically heterogeneous. We investigated deafness segregating as a recessive trait in two families. Audiological examinations revealed an asymmetric mild to profound hearing loss with childhood or adolescent onset. Exome sequencing… read more here.
Keywords: hearing loss; cldn9; mild profound; deafness ... See more keywords
Claudin-9 is a novel prognostic biomarker for endometrial cancer
Sign Up to like & getrecommendations! Published in 2022 at "International Journal of Oncology"
DOI: 10.3892/ijo.2022.5425
Abstract: The tight-junction protein claudin-9 (CLDN9) is barely distributed in normal adult tissues but is ectopically expressed in various cancer types. Although multiple databases indicated upregulation of CLDN9 in endometrial cancers at the mRNA level, its… read more here.
Keywords: endometrial cancer; cldn9 expression; high cldn9; cldn9 ... See more keywords