Articles with "clean btk" as a keyword



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A Fast and Clean BTK Inhibitor

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Published in 2020 at "Journal of Medicinal Chemistry"

DOI: 10.1021/acs.jmedchem.0c00597

Abstract: Bruton’s tyrosine kinase (BTK) is a major drug target for B-cell related malignancies; however, existing BTK inhibitors approved for cancer treatment have significant off-targets that limit their use for autoimmune and inflammatory diseases. Remibrutinib (LOU064)… read more here.

Keywords: clean btk; chemistry; btk; fast clean ... See more keywords