Adjuvant Therapy for Non-Clear Cell Renal Cell Carcinoma-The Ascent Continues.
Sign Up to like & getrecommendations! Published in 2024 at "JAMA network open"
DOI: 10.1001/jamanetworkopen.2024.25251
Abstract: Surgery is the preferred treatment for localized renal cell carcinoma (RCC). Although pursued with curative intent, approximately 50% of patients will experience disease recurrence. Pembrolizumab was approved as adjuvant treatment for patients at high risk… read more here.
Keywords: rcc; cell; cell carcinoma; clear cell ... See more keywords
APOBEC3C‐mediated NF‐κB activation enhances clear cell renal cell carcinoma progression
Sign Up to like & getrecommendations! Published in 2024 at "Molecular Oncology"
DOI: 10.1002/1878-0261.13721
Abstract: Renowned as the predominant form of kidney cancer, clear cell renal cell carcinoma (ccRCC) exhibits susceptibility to immunotherapies due to its specific expression profile as well as notable immune cell infiltration. Despite this, effectively treating… read more here.
Keywords: cell renal; cell; cell carcinoma; clear cell ... See more keywords
Single Atom‐Engineered 2D Catalytic Nanosheets for Sonocatalytic Suppression of Orthotopic Clear Cell Renal Cell Carcinoma
Sign Up to like & getrecommendations! Published in 2024 at "Advanced Functional Materials"
DOI: 10.1002/adfm.202414302
Abstract: Clear cell renal cell carcinoma (ccRCC), a prevalent malignant tumor, exhibits resistance to chemotherapy, necessitating advanced therapeutic approaches. Sonocatalytic therapy has emerged as a promising non‐invasive treatment for solid tumors due to its ability to… read more here.
Keywords: cell renal; cell; cell carcinoma; clear cell ... See more keywords
A Feedback Loop Between Fatty Acid Metabolism and Epigenetics in Clear Cell Renal Carcinoma
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DOI: 10.1002/advs.202504532
Abstract: Lipid storage and epigenetic dysregulation are key features for clear cell renal carcinoma (ccRCC). However, the interplay between fatty acid metabolism and epigenetics in ccRCC remains to be further demonstrated. Here, the landscape of active… read more here.
Keywords: acid metabolism; metabolism; renal carcinoma; clear cell ... See more keywords
Polystyrene Microplastics Exposure Aggravates Clear Cell Renal Cell Carcinoma Progression via the NF-κB and TGF-β Signaling Pathways.
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DOI: 10.1002/advs.202518500
Abstract: Polystyrene microplastics (PS-MPs) are increasingly associated with carcinogenesis. However, their specific role in clear cell renal cell carcinoma (ccRCC) remains unclear. In this study, the microplastics in ccRCC tissues and normal adjacent tissues (NAT) are… read more here.
Keywords: renal cell; progression; cell; polystyrene microplastics ... See more keywords
NAT10‐mediated ac4C‐modified ANKZF1 promotes tumor progression and lymphangiogenesis in clear‐cell renal cell carcinoma by attenuating YWHAE‐driven cytoplasmic retention of YAP1
Sign Up to like & getrecommendations! Published in 2024 at "Cancer Communications"
DOI: 10.1002/cac2.12523
Abstract: Lymphatic metastasis is one of the most common metastatic routes and indicates a poor prognosis in clear‐cell renal cell carcinoma (ccRCC). N‐acetyltransferase 10 (NAT10) is known to catalyze N4‐acetylcytidine (ac4C) modification of mRNA and participate… read more here.
Keywords: cell renal; cell; cell carcinoma; clear cell ... See more keywords
Knockdown of MAPK14 inhibits the proliferation and migration of clear cell renal cell carcinoma by downregulating the expression of CDC25B
Sign Up to like & getrecommendations! Published in 2019 at "Cancer Medicine"
DOI: 10.1002/cam4.2795
Abstract: Mitogen‐activated protein kinase 14 (MAPK14), which plays an important role in DNA damage and repair, is activated by various environmental stress and proinflammatory cytokines. It is highly active in a variety of tumors, acting as… read more here.
Keywords: proliferation migration; mapk14; cell; clear cell ... See more keywords
Comprehensive analysis of copy number variance and sensitivity to common targeted therapy in clear cell renal cell carcinoma: In silico analysis with in vitro validation
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DOI: 10.1002/cam4.3281
Abstract: Abstract Background Chromosomal rearrangements are common in clear cell renal cell carcinoma (ccRCC) and their roles in mediating sensitivity to tyrosine kinase inhibitors (TKIs) and mTOR inhibitors (mTORi) remain elusive. Methods We developed an in… read more here.
Keywords: analysis; sensitivity; cell; clear cell ... See more keywords
Patterns of distant metastases in patients with clear cell renal cell carcinoma––A population‐based analysis
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DOI: 10.1002/cam4.3596
Abstract: We developed this study to describe the patterns of distant metastasis (DM) and explore the predictive and prognostic factors of DM in clear cell renal cell carcinoma (ccRCC) patients. We collected the eligible patients from… read more here.
Keywords: cell renal; renal cell; cell carcinoma; patterns distant ... See more keywords
Construction of circRNA-based ceRNA network and its prognosis-associated subnet of clear cell renal cell carcinoma.
Sign Up to like & getrecommendations! Published in 2021 at "Cancer medicine"
DOI: 10.1002/cam4.4311
Abstract: Circular RNAs (circRNAs) are novel biomarkers of various cancers. CircRNAs can sponge miRNAs and regulate target mRNAs, which was called competing endogenous RNAs (ceRNA). This study was designed to identify circRNAs related to patients with… read more here.
Keywords: cell renal; renal cell; cell carcinoma; cerna network ... See more keywords
Characteristics of contrast-enhanced ultrasound for diagnosis of solid clear cell renal cell carcinomas ≤4 cm: A meta-analysis.
Sign Up to like & getrecommendations! Published in 2021 at "Cancer medicine"
DOI: 10.1002/cam4.4365
Abstract: Now solid renal tumors ≤4 cm is the most common, especially the subtype of clear cell renal cell carcinoma (ccRCC) of malignant kidney tumors in clinical. However, there is not specific characteristics of contrast-enhanced ultrasound (CEUS)… read more here.
Keywords: cell renal; contrast; cell; clear cell ... See more keywords