Autophagic Pathways to Clear the Tau Aggregates in Alzheimer’s Disease
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DOI: 10.1007/s10571-020-00897-0
Abstract: Tau is a microtubule-associated protein with an intrinsically unstructured conformation. Tau is subjected to several pathological post-translational modifications (PTMs), leading to its loss of interaction with microtubules and accumulation as neurofibrillary tangles (NFTs) in neurons.… read more here.
Keywords: degradation; tau; pathways clear; tau aggregates ... See more keywords